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Phendimetrazine
Systematic (IUPAC) name
3,4-dimethyl-2-phenylmorpholine
Identifiers
CAS number 634-03-7
ATC code none
PubChem 12460
Chemical data
Formula C 12H17NO 
Mol. mass 191.27 g/mol
Pharmacokinetic data
Bioavailability Peak plasma levels occur within 1 to 3 hours. Absorption is usually complete by 4 to 6 hours
Metabolism hepatic
Half life 19-24 hours
Excretion Urinary elimination
Therapeutic considerations
Pregnancy cat. C (US)
Legal status C-III (US)
Routes Oral
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Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.[1]

Contents

Pharmacology

Phendimetrazine functions as a prodrug to phenmetrazine, and approximately 30% of any given oral dose is converted into it. Phendimetrazine can essentially be thought of as an extended release and less abusable version of phenmetrazine. Phenmetrazine (and therefore phendimetrazine as well) acts as a norepinephrine-dopamine releasing agent (NDRA).[2]

Legality

Phendimetrazine.jpg

Phendimetrazine is as potent as amphetamine and is a Schedule III drug under the Convention on Psychotropic Substances. In the United States, phendimetrazine is a Schedule III controlled substance under the Uniform Controlled Substances Act of 1970.

According to the "List of psychotropic substances under international control", phendimetrazine is a Schedule IV controlled substance.[3] Phendimetrazine is listed as a Schedule III substance under the U.S. Controlled Substance Act in the 2007 Drug Identification Bible, pg 615 and under Section 11056(b)(6) California Health and Safety Code.

See also

References








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