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Phenylpiracetam: Wikis


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Systematic (IUPAC) name
CAS number 77472-70-9
ATC code none
PubChem 132441
Chemical data
Formula C 12H14N2O2  
Mol. mass 218.3 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability ~100 %
Metabolism  ?
Half life 3-5 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Legal to import
Routes Oral

Carphedon (C12H14N2O2, 2-(4-phenyl-2-oxopyrrolidin-1-yl)acetamide) is a derivative of the nootropic drug piracetam. It was developed in Russia, and a small number of low-scale clinical studies have shown possible links between prescription of carphedon and improvement in a number of encephalopathic conditions, including lesions of cerebral blood pathways, and certain types of glioma. It is also claimed to increase physical stamina and provide improved tolerance to cold. As a result, it appears on the lists of banned substances issued by the World Anti-Doping Agency. This list is applicable in all Olympic sports. As of 27 February 2006, the most recent confirmed case of carphedon abuse by a professional athlete is that of Russian biathlon Olympic silver medalist Olga Pyleva in the 2006 Winter Olympics, who was disqualified from attending further events following a positive drug test. She was subsequently banned from competition for two years. It may be noteworthy that Pyleva claims that carphedon was an unlisted ingredient of a Russian medication she was prescribed by her personal doctor (not a team doctor).

In August 2008, Russian steeplechase runner Roman Usov was pulled out of the Beijing Olympics for what media reported was a possible positive test for Carphedon[1].

A former rider for Gerolsteiner, professional cyclist Danilo Hondo, tested positive to this banned substance in 2005.

While not widely available in the West, in Russia it is available as a prescription medicine under the brand name "Phenotropil". Packets of ten 100 mg pills are available for roughly 350 rubles (2009 price), or about 10 USD. It is typically prescribed as a general stimulant or to increase tolerance to cold and stress.

See also


  1. ^ CNN, "Runners fail pre-Olympics doping tests", Retrieved on 2008-08-09

External links



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