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Phylloquinone: Wikis

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Phylloquinone
VitaminK1.png
IUPAC name
Identifiers
CAS number 84-80-0
PubChem 4812
SMILES
Properties
Molecular formula C31H46O2
Molar mass 450.7 g mol−1
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Phylloquinone is a polycyclic aromatic ketone, based on 2-methyl-1,4-naphthoquinone, with a 3-phytyl substituent.

It is a fat-soluble vitamin that is stable to air and moisture but decomposes in sunlight. It is found naturally in a wide variety of green plants.

Contents

Terminology

It is often called vitamin K1[1] or phytonadione. Sometimes a distinction is made with phylloquinone considered natural and phytonadione considered synthetic.[2]

A stereoisomer of phylloquinone is called vitamin k1 (note the difference in capitalization).

Mechanism

Its best known mechanism of action is as a cofactor in the formation of coagulation factors II (prothrombin), VII, IX and X by the liver. Vitamin K1 is commonly used to treat warfarin toxicity, and an antidote for coumatetralyl. It is also required for the formation of anticoagulant factors protein C and S. Vitamin K is also required bone protein formation.

Phylloquinone is an electron accepter in electron transport chain of chloroplasts.

See also

References

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