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Pivalylbenzhydrazine
Systematic (IUPAC) name
N'-benzyl-2,2-dimethyl-propanehydrazide
Identifiers
CAS number 306-19-4
ATC code  ?
PubChem 9375
ChemSpider 9007
Chemical data
Formula C12H18N2O
Mol. mass 206.28 g/mol
Synonyms Angorvid, Betamezid, Neomarsilid, Pivazide, Pivhydrazine
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Uncontrolled
Routes Oral

Pivalylbenzhydrazine (Tersavid), also known as pivazide and pivhydrazine, is an irreversible and nonselective monoamine oxidase inhibitor (MAOI) of the hydrazine chemical class that was previously used as an antidepressant in the 1960s, but has since been discontinued.[1][2][3]

See also

References

  1. ^ Herman ZS, Sokola A, Lenartowicz H, Zieliński M, Depta L (1976). "The influence of antidepressive drugs on the level of acetylcholine and on the acetylcholinesterase activity in the brain of rats". Polish Journal of Pharmacology and Pharmacy 28 (4): 313–21. PMID 981020.  
  2. ^ Bolton GC, Griffiths LA (1979). "The metabolic disposition of [14Cpivhydrazine, [14C]mebanazine, and [14C]benzylhydrazine in the rat"]. Drug Metabolism and Disposition: the Biological Fate of Chemicals 7 (6): 388–92. PMID 43225. http://dmd.aspetjournals.org/cgi/pmidlookup?view=long&pmid=43225.  
  3. ^ Mikhaĭlova TV, Gilev AP, Khavronina-Gureeva ZP (1969). "[Central effects of betamezide]" (in Russian). Farmakologiia I Toksikologiia 32 (6): 652–6. PMID 5381593.  







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