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Portmanteau inhibitor: Wikis


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A portmanteau inhibitor is a drug that is a combination of two drug molecules, each of which is itself a type of inhibitor. The term was coined in 2007 by University of Minnesota researchers who designed and synthesized a combination HIV Reverse transcriptase inhibitor and an Integrase inhibitor.[1][2][3]


  1. ^ "U of M researchers announce advance in treatment of HIV". 25 July 2007.  
  2. ^ "Researchers Discover New Method To Combat HIV". 25 July 2007.  
  3. ^ Zhengqiang Wang, Eric M. Bennett, Daniel J. Wilson, Christine Salomon, and Robert Vince (2007). "Rationally Designed Dual Inhibitors of HIV Reverse Transcriptase and Integrase" ( – Scholar search). Journal of Medicinal Chemistry 50 (15): 3416–3419. doi:10.1021/jm070512p. PMID 17608468.  


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