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Pranlukast: Wikis


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Systematic (IUPAC) name
ATC code R03DC02
PubChem 115100
Chemical data
Formula C27H23N5O4 
Mol. mass 481.503 g/mol
Pharmacokinetic data
Metabolism Hepatic (mainly CYP3A4)[1]
Half life 1.5 hours[1]
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral

Pranlukast is a cysteinyl leukotriene receptor-1 antagonist. This drug works similarly to Merck & Co.'s Singulair (montelukast). It is currently under clinical trials.

Medications of this class, which go under a variety of names according to whether one looks at the American, British or European system of nomenclature, have as their primary function the antagonism of bronchospasm caused, principally in asthmatics, by an allergic reaction to accidentally or inadvertently encountered allergens.

Medications of this group are normally used as an adjunct to the standard therapy of inhaled steroids with inhaled long- and/or short-acting beta-agonists. There are several similar medications in the group; all appear to be equally effective.




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