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Prazitone: Wikis


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Systematic (IUPAC) name
5-phenyl-5-(piperidin-2-ylmethyl)pyrimidine-2,4,6(1 H,3H,5H)-trione
CAS number 2409-26-9
ATC code none
PubChem 3050417
Chemical data
Formula C 16H19N3O3  
Mol. mass 301.34 g/mol
Synonyms Prazitone, AGN-511, 5-Phenyl-5-(2-piperidylmethyl)barbituric acid
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Prazitone (AGN-511) is a barbiturate derivative invented in the 1970s. Unlike most barbiturates, it has little or no sedative effects, instead acting as a non-sedating anxiolytic and antidepressant.[1] The dosage range in humans is around 200-600mg, although higher doses have been used in trials for the treatment of depression associated with Parkinson's disease.


  1. ^ Ross Langlands. Method for imparting anti-depressant and/or anxiolytic effects to animals. US Patent 3,806,596


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