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Procaterol: Wikis

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Procaterol
Systematic (IUPAC) name
8-Hydroxy-5-[1-hydroxy-2-(isopropylamino)butyl]-quinolin-2(1 H)-one
Identifiers
CAS number 59828-07-8
ATC code R03AC16 R03CC08
PubChem 4916
Chemical data
Formula C 16H22N2O3  
Mol. mass 290.357 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Oral, inhalation

Procaterol, applied as procaterol hydrochloride (USAN), is a short-acting β2-adrenergic receptor agonist used for the treatment of asthma. It has never been filed for FDA evaluation in the United States, where it is not marketed. The drug is readily oxidated in the presence of moisture and air, making it unsuitable for therapeutic use by inhalation.[1] Pharmaceutical company Parke-Davis/Warner-Lambert researched a stabilizer to prevent oxidation, but an effective one was never developed.[1]

References

  1. ^ a b Ghebre-sellassie, Issac & Russell U. Nesbitt Jr., "Procaterol stabilization", US 4616022, published 1984, issued 1986
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