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From Wikipedia, the free encyclopedia

Proctosedyl is the brand name for a family of two products with identical active ingredients designed to treat a variety of proctological disorders. One is a topical ointment, the other a rectal suppository. In the United Kingdom both products are contract manufactured by Patheon Limited on behalf of the Sanofi-Aventis group[1][2]. Manufacture and distribution is provided by Sanofi Aventis subsidiaries[3] Hoescht and Hoescht Marion Roussel in other territories worldwide.[4]

Contents

Application

Both the yellowish-white, translucent, greasy ointment[1] and the smooth, off-white suppositories[2] are formulated for the relief of chronic pruritus ani (otherwise known anal itching or anusitis)[1][2][5] and the treatment of pain, irritation, discharge and itching associated with haemorrhoids (otherwise known as piles)[1][2][5]. However both products are also used to provide pain relief in the treatment of anal fissure[6][7][8], for patients undergoing haemorrhoidectomy, (pre and post-operative)[8], in the relief of post-partum (otherwise known as post-natal) haemorrhoidal conditions,[9][8] and in the treatment of non-infective proctitis.[8]

Active Ingredients

Both preparations contain:

Preparations in some territories may also contain:

References

  1. ^ a b c d e f "Patient Information Leaflets Online: Proctosedyl Ointment: PL 04425/0207". http://xpil.medicines.org.uk/ViewPil.aspx?DocID=8301. Retrieved 2009-01-21.  
  2. ^ a b c d e f "Patient Information Leaflets Online: Proctosedyl Suppositories: PL 04425/0208". http://xpil.medicines.org.uk/ViewPil.aspx?DocID=8302. Retrieved 2009-01-21.  
  3. ^ "Sanofi Aventis: Hoescht Home Page". http://www.sanofi-aventis.de/live/de/de/layout.jsp?scat=AC603939-733B-4C0D-8AAB-0F6E3BF9B2B7. Retrieved 2009-01-22.  
  4. ^ a b c "The South African Medical Formulary: C05A Antihaemorrhoidals for topical use". http://web.uct.ac.za/depts/mmi/jmoodie/c05html.html. Retrieved 2009-01-22.  
  5. ^ a b "NetDoctor: Proctosedyl ointment/suppositories". http://www.netdoctor.co.uk/medicines/100002157.html. Retrieved 2009-01-21.  
  6. ^ Maan MS, Mishra R, Thomas S, Hadke NS (2004). "Randomized, double-blind trial comparing topical nitroglycerine with xylocaine and Proctosedyl in idiopathic chronic anal fissure". Indian Journal of Gastroenterology 23 (3): 91–3. PMID 15250565.  
  7. ^ "A general practitioner study to evaluate the efficacy of 'Proctosedyl' ointment in the treatment of acute fissure-in-ano". The British Journal of Clinical Practice 24 (7): 289–91. July 1970. PMID 4919315.  
  8. ^ a b c d e f "Medsafe: Information for Health Professionals: Proctosedyl". http://www.medsafe.govt.nz/Profs/datasheet/p/Proctosedylointsupp.htm. Retrieved 2009-01-21.  
  9. ^ Damianov L, Katsarova M (1993). "[Our experience in using the preparation Proctosedyl from the Roussel firm in pregnant women with hemorrhoids]" (in Bulgarian). Akusherstvo I Ginekologii͡a 32 (3): 71. PMID 8037333.  
  10. ^ Larsen PO (September 1992). "[The Danish fund for basic research--a new cigar-box]" (in Danish). Ugeskrift for Laeger 154 (39): 2657. PMID 1413190.  
  11. ^ Duncan SH, Leitch EC, Stanley KN, et al. (May 2004). "Effects of esculin and esculetin on the survival of Escherichia coli O157 in human faecal slurries, continuous-flow simulations of the rumen and colon and in calves". The British Journal of Nutrition 91 (5): 749–55. doi:10.1079/BJN20041101. PMID 15137927.  

External links

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