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Prokineticin receptor: Wikis

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prokineticin receptor 1
Identifiers
Symbol PROKR1
Alt. symbols GPR73
Entrez 10887
HUGO 4524
OMIM 607122
RefSeq NM_138964
UniProt Q8TCW9
Other data
Locus Chr. 2 p14
prokineticin receptor 2
Identifiers
Symbol PROKR2
Alt. symbols GPR73L1
Entrez 128674
HUGO 15836
OMIM 607123
RefSeq NM_144773
UniProt Q8NFJ6
Other data
Locus Chr. 20 p12.3

The prokineticin receptor is a G-protein coupled receptor which binds the peptide hormone prokineticin. There are two variants each encoded by a different gene (PROKR1, PROKR2).[1] These receptors mediate gastrointestinal smooth muscle contraction and angiogenesis.

References

  1. ^ Lin DC, Bullock CM, Ehlert FJ, Chen JL, Tian H, Zhou QY (2002). "Identification and molecular characterization of two closely related G protein-coupled receptors activated by prokineticins/endocrine gland vascular endothelial growth factor". J. Biol. Chem. 277 (22): 19276–80. doi:10.1074/jbc.M202139200. PMID 11886876.  

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