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Prostaglandin E: Wikis

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Updated live from Wikipedia, last check: May 26, 2013 08:39 UTC (36 seconds ago)

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PGE1 - Alprostadil
PGE2 - Dinoprostone

Prostaglandin E is a family of naturally occurring prostaglandins and may be used pharmaceutically in medicine.

Types include:

It is created from prostaglandin E synthase.

Prostaglandin E2

Prostaglandin E2 is secreted in microvessels by the endothelium. It is a direct vasodilator and it inhibits the release of noradrenaline from sympathetic nerve terminals. It doesn't have the effect on platelets PGI2 does.

References

Pharmacology 2007. Rang, Dale, Ritter, Flower. Churchill Livingstone Elsevier.

External links

Autacoids, unsaturated fatty acids: Eicosanoids
Precursor
Prostanoids
Precursor
Active
D/J
E/F
I
A2 · B2
Leukotrienes (LT)
Precursor
Initial
A4 · B4
C4 · D4 · E4
Nonclassic
By function

bronchoconstriction (PGF2α, TXA2, LTC4, LTD4, LTE4)

vasoconstriction (PGF2α, TXA2, TXB2) · vasodilation (PGE2, PGI2, LTC4, LTD4, LTE4)

platelets: induce (TXA2) inhibit (PGD2, PGI2) · leukocytes: induce (TXA2, LTB4) inhibit (PGD2, PGE2)

labor stimulation: (PGE2 (Dinoprostone), PGF2α (Dinoprost))
see also enzymes







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