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Proxibarbal: Wikis


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Systematic (IUPAC) name
5-allyl-5-(2-hydroxypropyl)pyrimidine-2,4,6(1 H,3H,5H)-trione
CAS number 2537-29-3
ATC code N05CA22
PubChem 17336
Chemical data
Formula C 10H14N2O4  
Mol. mass 226.229 g/mol
Synonyms Proxibarbital, Centralgol, Ipronal, 5-Allyl-5-(β-hydroxypropyl)barbituric acid
Pharmacokinetic data
Bioavailability  ?
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Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Proxibarbital (Ipronal) is a barbiturate derivative invented in the 1970s. It has sedative, hypnotic and anticonvulsant properties, and was used in the treatment of migraine headaches in a similar manner to butalbital.[1]


  1. ^ Sulman FG, Pfeifer Y, Tal E. Migraine therapy by enzyme induction with proxibarbital (German). Therapie die Gegenwart. 1976 Dec;115(12):2088-103.


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