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From Wikipedia, the free encyclopedia

Quipazine
Systematic (IUPAC) name
2-piperazin-1-ylquinoline
Identifiers
CAS number 4774-24-7
ATC code none
PubChem 5011
Chemical data
Formula C13H15N3 
Mol. mass 213.278 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Quipazine is a piperazine drug used in scientific research. It is a moderately selective serotonin receptor agonist, binding to a range of different serotonin receptors, but particularly to the 5-HT2A[1] and 5-HT3.[2]

See also

References

  1. ^ Smith RL, Barrett RJ, Sanders-Bush E. Neurochemical and behavioral evidence that quipazine-ketanserin discrimination is mediated by serotonin2A receptor. Journal of Pharmacology and Experimental Therapeutics. 1995 Nov;275(2):1050-7. PMID 7473132
  2. ^ Cappelli A, Anzini M, Vomero S, Mennuni L, Makovec F, Doucet E, Hamon M, Bruni G, Romeo MR, Menziani MC, De Benedetti PG, Langer T. Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 1. Mapping the central 5-HT3 receptor binding site by arylpiperazine derivatives. Journal of Medicinal Chemistry. 1998 Feb 26;41(5):728-41. PMID 9513601
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