The Full Wiki

More info on RACK protein

RACK protein: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

RACK is an acronym for Receptor for Activated C-Kinase and is responsible for the binding of active forms of the protein kinase C (PKC) family of enzymes. See also RICK, Receptor for Inactive C-Kinase.

There are different RACKs for different isoforms of PKC, which thus mediate differential subcellular targeting of the isoforms.

Inactive forms of PKC occlude the RACK binding site with a pseudo-RACK peptide sequence

RACKs share 47% identity with the beta subunit of G proteins

RACKs represent one of the many ways in which a cell can use signalling complexes to manipulate the specificity of interactions within intracellular signalling cascades








Got something to say? Make a comment.
Your name
Your email address
Message