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RS-56812: Wikis

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RS-56812
Systematic (IUPAC) name
N-[(3R)-1-azabicyclo[2.2.2]oct-3-yl]-2-(1-methyl-1 H-indol-3-yl)-2-oxoacetamide
Identifiers
CAS number 143137-35-3
ATC code  ?
PubChem 6604789
Chemical data
Formula C 18H21N3O2  
Mol. mass 311.377 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

RS-56812 is a potent and selective partial agonist at the 5HT3 receptor.[1] It has been shown to improve performance on animal tests of memory.[2]

References

  1. ^ Van Hooft JA, Vijverberg HP. RS-056812-198: partial agonist on native and antagonist on cloned 5-HT3 receptors. European Journal of Pharmacology. 1997 Mar 19;322(2-3):229-33. PMID 9098692
  2. ^ Terry AV Jr, Buccafusco JJ, Prendergast MA, Jackson WJ, Fontana DL, Wong EH, Whiting RL, Eglen RM. The 5-HT3 receptor antagonist, RS-56812, enhances delayed matching performance in monkeys. Neuroreport. 1996 Dec 20;8(1):49-54. PMID 9051751
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