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From Wikipedia, the free encyclopedia

Classification and external resources
ICD-10 L58.
ICD-9 692.82

Radiation dermatitis (also known as "Radiodermatitis") is a skin disease associated with prolonged exposure to radiation.[1]:131-2 Radiation dermatitis occurs to some degree in most patients receiving radiotherapy, with or without chemotherapy.[2]

There are three specific types of radiodermatitis: acute radiodermatitis, chronic radiodermatitis, and eosinophilic, polymorphic, and pruritic eruption associated with radiotherapy.[1]:39-40 However, radiation therapy may also lead to radiation cancer.[1]:40

With interventional fluoroscopy, becasuse of the high skin doses that can be generated in the course of the intervention, some procedures have resulted in early (less than 2months after exposure) and/or late (2months or more after exposure) skin reactions, including necrosis in some cases.[3]:773

Radiation dermatitis, in the form of intense erythema and vesiculation of the skin, may be observed in radiation ports.[1]:131

As many as 95% of patients treated with radiation therapy for cancer will experience a skin reaction. Some reactions are immediate, while others may be later (e.g., months after treatment).[4]

See also


  1. ^ a b c d James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0721629210.
  2. ^ Bernier J, Bonner J, Vermorken JB, et al. (January 2008). "Consensus guidelines for the management of radiation dermatitis and coexisting acne-like rash in patients receiving radiotherapy plus EGFR inhibitors for the treatment of squamous cell carcinoma of the head and neck". Ann. Oncol. 19 (1): 142–9. doi:10.1093/annonc/mdm400. PMID 17785763. 
  3. ^ Wagner LK, McNeese MD, Marx MV, Siegel EL (December 1999). "Severe skin reactions from interventional fluoroscopy: case report and review of the literature". Radiology 213 (3): 773–6. PMID 10580952. 
  4. ^ Porock D, Nikoletti S, Kristjanson L (1999). "Management of radiation skin reactions: literature review and clinical application". Plast Surg Nurs 19 (4): 185–92, 223; quiz 191–2. PMID 12024597. 


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