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Relaxin/insulin-like family peptide receptor 3: Wikis


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Relaxin/insulin-like family peptide receptor 3
Symbols RXFP3; GPCR135; MGC141998; MGC142000; RLN3R1; SALPR
External IDs OMIM609445 MGI2441827 HomoloGene9568 IUPHAR: RXFP3 GeneCards: RXFP3 Gene
RNA expression pattern
PBB GE RXFP3 221066 at tn.png
More reference expression data
Species Human Mouse
Entrez 51289 239336
Ensembl ENSG00000182631 ENSMUSG00000060735
UniProt Q9NSD7 Q5Y988
RefSeq (mRNA) NM_016568 NM_178717
RefSeq (protein) NP_057652 NP_848832
Location (UCSC) Chr 5:
33.97 - 33.97 Mb
Chr 15:
10.98 - 10.98 Mb
PubMed search [1] [2]

Relaxin/insulin-like family peptide receptor 3, also known as RXFP3, is a human G-protein coupled receptor.[1]


See also


External links

Further reading

  • Bathgate RA, Ivell R, Sanborn BM, et al. (2005). "Receptors for relaxin family peptides.". Ann. N. Y. Acad. Sci. 1041: 61–76. doi:10.1196/annals.1282.010. PMID 15956688.  
  • Bathgate RA, Ivell R, Sanborn BM, et al. (2006). "International Union of Pharmacology LVII: recommendations for the nomenclature of receptors for relaxin family peptides.". Pharmacol. Rev. 58 (1): 7–31. doi:10.1124/pr.58.1.9. PMID 16507880.  
  • Matsumoto M, Kamohara M, Sugimoto T, et al. (2000). "The novel G-protein coupled receptor SALPR shares sequence similarity with somatostatin and angiotensin receptors.". Gene 248 (1-2): 183–9. doi:10.1016/S0378-1119(00)00123-2. PMID 10806363.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Liu C, Eriste E, Sutton S, et al. (2004). "Identification of relaxin-3/INSL7 as an endogenous ligand for the orphan G-protein-coupled receptor GPCR135.". J. Biol. Chem. 278 (50): 50754–64. doi:10.1074/jbc.M308995200. PMID 14522968.  
  • Liu C, Chen J, Kuei C, et al. (2005). "Relaxin-3/insulin-like peptide 5 chimeric peptide, a selective ligand for G protein-coupled receptor (GPCR)135 and GPCR142 over leucine-rich repeat-containing G protein-coupled receptor 7.". Mol. Pharmacol. 67 (1): 231–40. doi:10.1124/mol.104.006700. PMID 15465925.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Van der Westhuizen ET, Sexton PM, Bathgate RA, Summers RJ (2005). "Responses of GPCR135 to human gene 3 (H3) relaxin in CHO-K1 cells determined by microphysiometry.". Ann. N. Y. Acad. Sci. 1041: 332–7. doi:10.1196/annals.1282.053. PMID 15956730.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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