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Remoxipride: Wikis

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Remoxipride
Systematic (IUPAC) name
(S)-3-Bromo-N-[(1-ethylpyrrolidin-2-yl)methyl]-2,6-dimethoxy-benzamide
Identifiers
CAS number 117591-79-4
ATC code N05AL04
PubChem 54477
DrugBank DB00409
Chemical data
Formula C 16H23BrN2O3  
Mol. mass 371.27 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Remoxipride is a psychoactive drug and substituted benzamide which was a promising antipsychotic during clinical trials in the 1990s, but was removed due to possible side effects.

Remoxipride is a selective D2 receptor antagonist, with a relatively low effective dosage and low incidence of side effects relative to haloperidol. However, after its introduction in Europe, its use was correlated with incidence of aplastic anemia in as many as 1 in 10,000 cases, and it was taken off the market until its relationship to this possible side effect could be studied.

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