Dzerigian, a painter, was born to an Armenian family in Fresno, California and graduated in 2002 from California State University, Fresno. His work has been exhibited in solo and group shows in California and New York. He has been characterized as a neo-Dadaist, although there are Neo-romantic and mystical elements to his aesthetic orientation.
He is the son of fine-art photographer Steve Dzerigian. Ronald Dzerigian is also a musician and has played electric bass and sung with pop-rock bands. He is related (a cousin) to guitarist John Dzerigian, who toured with 1970s-era rock bands and recorded with fellow guitarists Jerry Garcia and Link Wray.