The Full Wiki

More info on SCN2B

SCN2B: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
Sodium channel, voltage-gated, type II, beta
Identifiers
Symbols SCN2B;
External IDs OMIM601327 MGI106921 HomoloGene3373 GeneCards: SCN2B Gene
RNA expression pattern
PBB GE SCN2B 210364 at tn.png
PBB GE SCN2B 210363 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6327 72821
Ensembl ENSG00000149575 ENSMUSG00000070304
UniProt O60939 Q1MXF8
RefSeq (mRNA) NM_004588 NM_001014761
RefSeq (protein) NP_004579 NP_001014761
Location (UCSC) Chr 11:
117.54 - 117.55 Mb
Chr 9:
44.87 - 44.88 Mb
PubMed search [1] [2]

Sodium channel subunit beta-2 is a protein that in humans is encoded by the SCN2B gene.[1][2]

Contents

See also

References

  1. ^ Plummer NW, Meisler MH (May 1999). "Evolution and diversity of mammalian sodium channel genes". Genomics 57 (2): 323-31. doi:10.1006/geno.1998.5735. PMID 10198179.  
  2. ^ "Entrez Gene: SCN2B sodium channel, voltage-gated, type II, beta". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6327.  

Further reading

  • Hartshorne RP, Catterall WA (1984). "The sodium channel from rat brain. Purification and subunit composition.". J. Biol. Chem. 259 (3): 1667–75. PMID 6319405.  
  • Adams MD, Kerlavage AR, Fleischmann RD, et al. (1995). "Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.". Nature 377 (6547 Suppl): 3–174. PMID 7566098.  
  • Isom LL, Ragsdale DS, De Jongh KS, et al. (1996). "Structure and function of the beta 2 subunit of brain sodium channels, a transmembrane glycoprotein with a CAM motif.". Cell 83 (3): 433–42. doi:10.1016/0092-8674(95)90121-3. PMID 8521473.  
  • Eubanks J, Srinivasan J, Dinulos MB, et al. (1997). "Structure and chromosomal localization of the beta2 subunit of the human brain sodium channel.". Neuroreport 8 (12): 2775–9. doi:10.1097/00001756-199708180-00025. PMID 9295116.  
  • Bolino A, Seri M, Caroli F, et al. (1999). "Exclusion of the SCN2B gene as candidate for CMT4B.". Eur. J. Hum. Genet. 6 (6): 629–34. doi:10.1038/sj.ejhg.5200220. PMID 9887383.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Clark HF, Gurney AL, Abaya E, et al. (2003). "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMID 12975309.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Kim DY, Ingano LA, Carey BW, et al. (2005). "Presenilin/gamma-secretase-mediated cleavage of the voltage-gated sodium channel beta2-subunit regulates cell adhesion and migration.". J. Biol. Chem. 280 (24): 23251–61. doi:10.1074/jbc.M412938200. PMID 15833746.  

External links

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message