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SLC25A11: Wikis


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Solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Symbols SLC25A11; OGC; SLC20A4
External IDs OMIM604165 MGI1915113 HomoloGene2637 GeneCards: SLC25A11 Gene
RNA expression pattern
PBB GE SLC25A11 209003 at tn.png
PBB GE SLC25A11 207088 s at tn.png
More reference expression data
Species Human Mouse
Entrez 8402 67863
Ensembl ENSG00000108528 ENSMUSG00000014606
UniProt Q02978 Q5SX46
RefSeq (mRNA) NM_003562 NM_024211
RefSeq (protein) NP_003553 NP_077173
Location (UCSC) Chr 17:
4.78 - 4.78 Mb
Chr 11:
70.46 - 70.46 Mb
PubMed search [1] [2]

Mitochondrial 2-oxoglutarate/malate carrier protein is a protein that in humans is encoded by the SLC25A11 gene.[1][2][3]

See also


  1. ^ Piccininni S, Iacobazzi V, Lauria G, Rocchi M, Palmieri F (Mar 1999). "Assignment of the oxoglutarate carrier gene (SLC20A4) to human chromosome 17p13.3". Cytogenet Cell Genet 83 (3-4): 256-7. PMID 10072597.  
  2. ^ Iacobazzi V, Palmieri F, Runswick MJ, Walker JE (Jan 1993). "Sequences of the human and bovine genes for the mitochondrial 2-oxoglutarate carrier". DNA Seq 3 (2): 79-88. PMID 1457818.  
  3. ^ "Entrez Gene: SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11".  

Further reading

  • Bisaccia F, Zara V, Capobianco L, et al. (1996). "The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier.". Biochim. Biophys. Acta 1292 (2): 281–88. PMID 8597574.  
  • Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.  
  • Bisaccia F, Capobianco L, Mazzeo M, Palmieri F (1996). "The mitochondrial oxoglutarate carrier protein contains a disulfide bridge between intramembranous cysteines 221 and 224.". FEBS Lett. 392 (1): 54–8. doi:10.1016/0014-5793(96)00784-3. PMID 8769314.  
  • Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. PMID 9110174.  
  • Palmisano A, Zara V, Hönlinger A, et al. (1998). "Targeting and assembly of the oxoglutarate carrier: general principles for biogenesis of carrier proteins of the mitochondrial inner membrane.". Biochem. J. 333 ( Pt 1): 151–8. PMID 9639574.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Coll O, Colell A, García-Ruiz C, et al. (2003). "Sensitivity of the 2-oxoglutarate carrier to alcohol intake contributes to mitochondrial glutathione depletion.". Hepatology 38 (3): 692–702. doi:10.1053/jhep.2003.50351. PMID 12939596.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  
  • Kabe Y, Ohmori M, Shinouchi K, et al. (2006). "Porphyrin accumulation in mitochondria is mediated by 2-oxoglutarate carrier.". J. Biol. Chem. 281 (42): 31729–35. doi:10.1074/jbc.M604729200. PMID 16920706.  


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