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SLC25A12: Wikis

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Solute carrier family 25 (mitochondrial carrier, Aralar), member 12
Identifiers
Symbols SLC25A12; ARALAR; ARALAR1
External IDs OMIM603667 MGI1926080 HomoloGene48235 GeneCards: SLC25A12 Gene
RNA expression pattern
PBB GE SLC25A12 203340 s at tn.png
PBB GE SLC25A12 203339 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 8604 78830
Ensembl ENSG00000115840 ENSMUSG00000027010
UniProt O75746 Q8BH59
RefSeq (mRNA) NM_003705 NM_172436
RefSeq (protein) NP_003696 NP_766024
Location (UCSC) Chr 2:
172.35 - 172.46 Mb
Chr 2:
71.07 - 71.17 Mb
PubMed search [1] [2]

Calcium-binding mitochondrial carrier protein Aralar1 is a protein that in humans is encoded by the SLC25A12 gene.[1][2][3][4]

See also

References

  1. ^ del Arco A, Satrustegui J (Oct 1998). "Molecular cloning of Aralar, a new member of the mitochondrial carrier superfamily that binds calcium and is present in human muscle and brain". J Biol Chem 273 (36): 23327-34. PMID 9722566.  
  2. ^ Crackower MA, Sinasac DS, Lee JR, Herbrick JA, Tsui LC, Scherer SW (Apr 2000). "Assignment of the SLC25A12 gene coding for the human calcium-binding mitochondrial solute carrier protein aralar to human chromosome 2q24". Cytogenet Cell Genet 87 (3-4): 197-8. PMID 10702666.  
  3. ^ Palmieri L, Pardo B, Lasorsa FM, del Arco A, Kobayashi K, Iijima M, Runswick MJ, Walker JE, Saheki T, Satrustegui J, Palmieri F (Sep 2001). "Citrin and aralar1 are Ca(2+)-stimulated aspartate/glutamate transporters in mitochondria". EMBO J 20 (18): 5060-9. doi:10.1093/emboj/20.18.5060. PMID 11566871.  
  4. ^ "Entrez Gene: SLC25A12 solute carrier family 25 (mitochondrial carrier, Aralar), member 12". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8604.  

Further reading

  • Kobayashi K, Sinasac DS, Iijima M, et al. (1999). "The gene mutated in adult-onset type II citrullinaemia encodes a putative mitochondrial carrier protein.". Nat. Genet. 22 (2): 159–63. doi:10.1038/9667. PMID 10369257.  
  • Sanz R, del Arco A, Ayuso C, et al. (2000). "Assignment of the calcium-binding mitochondrial carrier Aralar1 gene (SLC25A12) to human chromosome band 2q31 by in situ hybridization.". Cytogenet. Cell Genet. 89 (3-4): 143–4. doi:10.1159/000015595. PMID 10965105.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Ramoz N, Reichert JG, Smith CJ, et al. (2004). "Linkage and association of the mitochondrial aspartate/glutamate carrier SLC25A12 gene with autism.". The American journal of psychiatry 161 (4): 662–9. doi:10.1176/appi.ajp.161.4.662. PMID 15056512.  
  • Rubi B, del Arco A, Bartley C, et al. (2005). "The malate-aspartate NADH shuttle member Aralar1 determines glucose metabolic fate, mitochondrial activity, and insulin secretion in beta cells.". J. Biol. Chem. 279 (53): 55659–66. doi:10.1074/jbc.M409303200. PMID 15494407.  
  • Rabionet R, McCauley JL, Jaworski JM, et al. (2006). "Lack of association between autism and SLC25A12.". The American journal of psychiatry 163 (5): 929–31. doi:10.1176/appi.ajp.163.5.929. PMID 16648338.  
  • Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry.". Mol. Syst. Biol. 3: 89. doi:10.1038/msb4100134. PMID 17353931.  
  • Hong CJ, Liou YJ, Liao DL, et al. (2007). "Association study of polymorphisms in the mitochondrial aspartate/glutamate carrier SLC25A12 (aralar) gene with schizophrenia.". Prog. Neuropsychopharmacol. Biol. Psychiatry 31 (7): 1510–3. doi:10.1016/j.pnpbp.2007.07.010. PMID 17693006.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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