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Solute carrier family 32 (GABA vesicular transporter), member 1
Identifiers
Symbols SLC32A1; VGAT; VIAAT
External IDs MGI1194488 HomoloGene56451 GeneCards: SLC32A1 Gene
RNA expression pattern
PBB GE SLC32A1 gnf1h08592 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 140679 22348
Ensembl ENSG00000101438 ENSMUSG00000037771
UniProt Q9H598 Q49S98
RefSeq (mRNA) NM_080552 XM_979351
RefSeq (protein) NP_542119 XP_984445
Location (UCSC) Chr 20:
36.79 - 36.79 Mb
Chr 2:
158.3 - 158.31 Mb
PubMed search [1] [2]

Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.[1]

The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.[1]

See also

References

Further reading

  • McIntire SL, Reimer RJ, Schuske K, et al. (1997). "Identification and characterization of the vesicular GABA transporter.". Nature 389 (6653): 870–6. doi:10.1038/39908. PMID 9349821.  
  • Kleiderlein JJ, Nisson PE, Jessee J, et al. (1999). "CCG repeats in cDNAs from human brain.". Hum. Genet. 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901.  
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.  
  • Chessler SD, Simonson WT, Sweet IR, Hammerle LP (2002). "Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets.". Diabetes 51 (6): 1763–71. doi:10.2337/diabetes.51.6.1763. PMID 12031963.  
  • Jellali A, Stussi-Garaud C, Gasnier B, et al. (2002). "Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.". J. Comp. Neurol. 449 (1): 76–87. doi:10.1002/cne.10272. PMID 12115694.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Geigerseder C, Doepner R, Thalhammer A, et al. (2003). "Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors.". Neuroendocrinology 77 (5): 314–23. doi:10.1159/000070897. PMID 12806177.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
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