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SLC32A1: Wikis


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Solute carrier family 32 (GABA vesicular transporter), member 1
Symbols SLC32A1; VGAT; VIAAT
External IDs MGI1194488 HomoloGene56451 GeneCards: SLC32A1 Gene
RNA expression pattern
PBB GE SLC32A1 gnf1h08592 at tn.png
More reference expression data
Species Human Mouse
Entrez 140679 22348
Ensembl ENSG00000101438 ENSMUSG00000037771
UniProt Q9H598 Q49S98
RefSeq (mRNA) NM_080552 XM_979351
RefSeq (protein) NP_542119 XP_984445
Location (UCSC) Chr 20:
36.79 - 36.79 Mb
Chr 2:
158.3 - 158.31 Mb
PubMed search [1] [2]

Vesicular inhibitory amino acid transporter is a protein that in humans is encoded by the SLC32A1 gene.[1]

The protein encoded by this gene is an integral membrane protein involved in gamma-aminobutyric acid (GABA) and glycine uptake into synaptic vesicles. The encoded protein is a member of amino acid/polyamine transporter family II.[1]

See also


Further reading

  • McIntire SL, Reimer RJ, Schuske K, et al. (1997). "Identification and characterization of the vesicular GABA transporter.". Nature 389 (6653): 870–6. doi:10.1038/39908. PMID 9349821.  
  • Kleiderlein JJ, Nisson PE, Jessee J, et al. (1999). "CCG repeats in cDNAs from human brain.". Hum. Genet. 103 (6): 666–73. doi:10.1007/s004390050889. PMID 9921901.  
  • Deloukas P, Matthews LH, Ashurst J, et al. (2002). "The DNA sequence and comparative analysis of human chromosome 20.". Nature 414 (6866): 865–71. doi:10.1038/414865a. PMID 11780052.  
  • Chessler SD, Simonson WT, Sweet IR, Hammerle LP (2002). "Expression of the vesicular inhibitory amino acid transporter in pancreatic islet cells: distribution of the transporter within rat islets.". Diabetes 51 (6): 1763–71. doi:10.2337/diabetes.51.6.1763. PMID 12031963.  
  • Jellali A, Stussi-Garaud C, Gasnier B, et al. (2002). "Cellular localization of the vesicular inhibitory amino acid transporter in the mouse and human retina.". J. Comp. Neurol. 449 (1): 76–87. doi:10.1002/cne.10272. PMID 12115694.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Geigerseder C, Doepner R, Thalhammer A, et al. (2003). "Evidence for a GABAergic system in rodent and human testis: local GABA production and GABA receptors.". Neuroendocrinology 77 (5): 314–23. doi:10.1159/000070897. PMID 12806177.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  


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