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SLC34A2: Wikis


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Solute carrier family 34 (sodium phosphate), member 2
Symbols SLC34A2; FLJ90534; NAPI-3B; NAPI-IIb; NPTIIb
External IDs OMIM604217 MGI1342284 HomoloGene2297 GeneCards: SLC34A2 Gene
RNA expression pattern
PBB GE SLC34A2 204124 at tn.png
More reference expression data
Species Human Mouse
Entrez 10568 20531
Ensembl ENSG00000157765 ENSMUSG00000029188
UniProt O95436 Q9DBP0
RefSeq (mRNA) NM_006424 NM_011402
RefSeq (protein) NP_006415 NP_035532
Location (UCSC) Chr 4:
25.27 - 25.29 Mb
Chr 5:
53.34 - 53.36 Mb
PubMed search [1] [2]

Sodium-dependent phosphate transport protein 2B is a protein that in humans is encoded by the SLC34A2 gene.[1][2][3]

See also


  1. ^ Feild JA, Zhang L, Brun KA, Brooks DP, Edwards RM (Jun 1999). "Cloning and functional characterization of a sodium-dependent phosphate transporter expressed in human lung and small intestine". Biochem Biophys Res Commun 258 (3): 578-82. doi:10.1006/bbrc.1999.0666. PMID 10329428.  
  2. ^ Xu H, Bai L, Collins JF, Ghishan FK (Feb 2000). "Molecular cloning, functional characterization, tissue distribution, and chromosomal localization of a human, small intestinal sodium-phosphate (Na+-Pi) transporter (SLC34A2)". Genomics 62 (2): 281-4. doi:10.1006/geno.1999.6009. PMID 10610722.  
  3. ^ "Entrez Gene: SLC34A2 solute carrier family 34 (sodium phosphate), member 2".  

Further reading

  • Xu H, Collins JF, Bai L, et al. (2001). "Regulation of the human sodium-phosphate cotransporter NaP(i)-IIb gene promoter by epidermal growth factor.". Am. J. Physiol., Cell Physiol. 280 (3): C628–36. PMID 11171583.  
  • Segawa H, Kaneko I, Takahashi A, et al. (2002). "Growth-related renal type II Na/Pi cotransporter.". J. Biol. Chem. 277 (22): 19665–72. doi:10.1074/jbc.M200943200. PMID 11880379.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Xu H, Uno JK, Inouye M, et al. (2005). "NF1 transcriptional factor(s) is required for basal promoter activation of the human intestinal NaPi-IIb cotransporter gene.". Am. J. Physiol. Gastrointest. Liver Physiol. 288 (2): G175–81. doi:10.1152/ajpgi.00396.2004. PMID 15458926.  
  • Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  
  • Corut A, Senyigit A, Ugur SA, et al. (2006). "Mutations in SLC34A2 cause pulmonary alveolar microlithiasis and are possibly associated with testicular microlithiasis.". Am. J. Hum. Genet. 79 (4): 650–6. doi:10.1086/508263. PMID 16960801.  
  • Huqun , Izumi S, Miyazawa H, et al. (2007). "Mutations in the SLC34A2 gene are associated with pulmonary alveolar microlithiasis.". Am. J. Respir. Crit. Care Med. 175 (3): 263–8. doi:10.1164/rccm.200609-1274OC. PMID 17095743.  


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