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SLC4A2: Wikis


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Solute carrier family 4, anion exchanger, member 2 (erythrocyte membrane protein band 3-like 1)
Symbols SLC4A2; AE2; BND3L; EPB3L1; HKB3; NBND3
External IDs OMIM109280 MGI109351 HomoloGene31125 GeneCards: SLC4A2 Gene
RNA expression pattern
PBB GE SLC4A2 202111 at tn.png
More reference expression data
Species Human Mouse
Entrez 6522 20535
Ensembl ENSG00000164889 ENSMUSG00000028962
UniProt P04920 O54944
RefSeq (mRNA) NM_003040 NM_009207
RefSeq (protein) NP_003031 NP_033233
Location (UCSC) Chr 7:
150.39 - 150.4 Mb
Chr 5:
23.94 - 23.95 Mb
PubMed search [1] [2]

Anion exchange protein 2 is a protein that in humans is encoded by the SLC4A2 gene.[1][2]

See also


Further reading

  • Gehrig H, Müller W, Appelhans H (1992). "Complete nucleotide sequence of band 3 related anion transport protein AE2 from human kidney.". Biochim. Biophys. Acta 1130 (3): 326–8. PMID 1562608.  
  • Korsgren C, Cohen CM (1988). "Associations of human erythrocyte band 4.2. Binding to ankyrin and to the cytoplasmic domain of band 3.". J. Biol. Chem. 263 (21): 10212–8. PMID 2968981.  
  • Demuth DR, Showe LC, Ballantine M, et al. (1986). "Cloning and structural characterization of a human non-erythroid band 3-like protein.". Embo J. 5 (6): 1205–14. PMID 3015590.  
  • Palumbo AP, Isobe M, Huebner K, et al. (1986). "Chromosomal localization of a human band 3-like gene to region 7q35----7q36.". Am. J. Hum. Genet. 39 (3): 307–16. PMID 3020980.  
  • Rybicki AC, Musto S, Schwartz RS (1995). "Identification of a band-3 binding site near the N-terminus of erythrocyte membrane protein 4.2.". Biochem. J. 309 ( Pt 2): 677–81. PMID 7626035.  
  • Havenga MJ, Bosman GJ, Appelhans H, De Grip WJ (1995). "Expression of the anion exchanger (AE) gene family in human brain. Identification of a new AE protein: AE0.". Brain Res. Mol. Brain Res. 25 (1-2): 97–104. doi:10.1016/0169-328X(94)90283-6. PMID 7984058.  
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery.". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.  
  • Medina JF, Acín A, Prieto J (1997). "Molecular cloning and characterization of the human AE2 anion exchanger (SLC4A2) gene.". Genomics 39 (1): 74–85. doi:10.1006/geno.1996.4467. PMID 9027488.  
  • García C, Montuenga LM, Medina JF, Prieto J (1998). "In situ detection of AE2 anion-exchanger mRNA in the human liver.". Cell Tissue Res. 291 (3): 481–8. doi:10.1007/s004410051017. PMID 9477304.  
  • Jöns T, Drenckhahn D (1998). "Anion exchanger 2 (AE2) binds to erythrocyte ankyrin and is colocalized with ankyrin along the basolateral plasma membrane of human gastric parietal cells.". Eur. J. Cell Biol. 75 (3): 232–6. PMID 9587054.  
  • Mobasheri A, Golding S, Pagakis SN, et al. (1999). "Expression of cation exchanger NHE and anion exchanger AE isoforms in primary human bone-derived osteoblasts.". Cell Biol. Int. 22 (7-8): 551–62. doi:10.1006/cbir.1998.0299. PMID 10452823.  
  • Hyde K, Harrison D, Hollingsworth MA, Harris A (1999). "Chloride-bicarbonate exchangers in the human fetal pancreas.". Biochem. Biophys. Res. Commun. 263 (2): 315–21. doi:10.1006/bbrc.1999.1367. PMID 10491290.  
  • Holappa K, Mustonen M, Parvinen M, et al. (1999). "Primary structure of a sperm cell anion exchanger and its messenger ribonucleic acid expression during spermatogenesis.". Biol. Reprod. 61 (4): 981–6. doi:10.1095/biolreprod61.4.981. PMID 10491633.  
  • Karet FE, Finberg KE, Nayir A, et al. (2000). "Localization of a gene for autosomal recessive distal renal tubular acidosis with normal hearing (rdRTA2) to 7q33-34.". Am. J. Hum. Genet. 65 (6): 1656–65. doi:10.1086/302679. PMID 10577919.  
  • Medina JF, Lecanda J, Acín A, et al. (2000). "Tissue-specific N-terminal isoforms from overlapping alternate promoters of the human AE2 anion exchanger gene.". Biochem. Biophys. Res. Commun. 267 (1): 228–35. doi:10.1006/bbrc.1999.1951. PMID 10623603.  
  • Vince JW, Reithmeier RA (2000). "Identification of the carbonic anhydrase II binding site in the Cl(-)/HCO(3)(-) anion exchanger AE1.". Biochemistry 39 (18): 5527–33. doi:10.1021/bi992564p. PMID 10820026.  
  • Holappa K, Suokas M, Soininen P, Kellokumpu S (2001). "Identification of the full-length AE2 (AE2a) isoform as the Golgi-associated anion exchanger in fibroblasts.". J. Histochem. Cytochem. 49 (2): 259–69. PMID 11156694.  
  • Soleimani M, Greeley T, Petrovic S, et al. (2001). "Pendrin: an apical Cl-/OH-/HCO3- exchanger in the kidney cortex.". Am. J. Physiol. Renal Physiol. 280 (2): F356–64. PMID 11208611.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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