The Full Wiki

More info on SLC5A3

SLC5A3: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

edit
Solute carrier family 5 (inositol transporters), member 3
Identifiers
Symbols SLC5A3; SMIT; SMIT2
External IDs OMIM600444 MGI1858226 HomoloGene31412 GeneCards: SLC5A3 Gene
Orthologs
Species Human Mouse
Entrez 6526 53881
Ensembl n/a n/a
UniProt n/a n/a
RefSeq (mRNA) NM_006933 NM_017391
RefSeq (protein) NP_008864 NP_059087
Location (UCSC) n/a n/a
PubMed search [1] [2]

Sodium/myo-inositol cotransporter is a protein that in humans is encoded by the SLC5A3 gene.[1][2]

See also

References

  1. ^ Berry GT, Mallee JJ, Kwon HM, Rim JS, Mulla WR, Muenke M, Spinner NB (Jul 1995). "The human osmoregulatory Na+/myo-inositol cotransporter gene (SLC5A3): molecular cloning and localization to chromosome 21". Genomics 25 (2): 507-13. PMID 7789985.  
  2. ^ "Entrez Gene: SLC5A3 solute carrier family 5 (inositol transporters), member 3". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6526.  

Further reading

  • Kwon HM, Yamauchi A, Uchida S, et al. (1992). "Cloning of the cDNa for a Na+/myo-inositol cotransporter, a hypertonicity stress protein.". J. Biol. Chem. 267 (9): 6297–301. PMID 1372904.  
  • Berry GT, Mallee JJ, Blouin JL, Antonarakis SE (1996). "The 21q22.1 STS marker, VN02 (EST00541 cDNA), is part of the 3' sequence of the human Na+/myo-inositol cotransporter (SLC5A3) gene.". Cytogenet. Cell Genet. 73 (1-2): 77–8. doi:10.1159/000134311. PMID 8646889.  
  • Mallee JJ, Atta MG, Lorica V, et al. (1998). "The structural organization of the human Na+/myo-inositol cotransporter (SLC5A3) gene and characterization of the promoter.". Genomics 46 (3): 459–65. doi:10.1006/geno.1997.5055. PMID 9441750.  
  • Porcellati F, Hlaing T, Togawa M, et al. (1998). "Human Na(+)-myo-inositol cotransporter gene: alternate splicing generates diverse transcripts.". Am. J. Physiol. 274 (5 Pt 1): C1215–25. PMID 9612208.  
  • Rim JS, Atta MG, Dahl SC, et al. (1998). "Transcription of the sodium/myo-inositol cotransporter gene is regulated by multiple tonicity-responsive enhancers spread over 50 kilobase pairs in the 5'-flanking region.". J. Biol. Chem. 273 (32): 20615–21. doi:10.1074/jbc.273.32.20615. PMID 9685419.  
  • Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21.". Nature 405 (6784): 311–9. doi:10.1038/35012518. PMID 10830953.  
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.  
  • Suzuki Y, Yamashita R, Shirota M, et al. (2004). "Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.". Genome Res. 14 (9): 1711–8. doi:10.1101/gr.2435604. PMID 15342556.  
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMID 16344560.  
  • Thangaraju M, Gopal E, Martin PM, et al. (2007). "SLC5A8 triggers tumor cell apoptosis through pyruvate-dependent inhibition of histone deacetylases.". Cancer Res. 66 (24): 11560–4. doi:10.1158/0008-5472.CAN-06-1950. PMID 17178845.  
Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message