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SLC7A4: Wikis


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Solute carrier family 7 (cationic amino acid transporter, y+ system), member 4
Symbols SLC7A4; VH; CAT-4; CAT4; HCAT3; MGC129976; MGC129977
External IDs OMIM603752 MGI2146512 HomoloGene20883 GeneCards: SLC7A4 Gene
RNA expression pattern
PBB GE SLC7A4 214406 s at tn.png
PBB GE SLC7A4 205864 at tn.png
More reference expression data
Species Human Mouse
Entrez 6545 224022
Ensembl ENSG00000099960 ENSMUSG00000022756
UniProt O43246 n/a
RefSeq (mRNA) NM_004173 NM_144852
RefSeq (protein) NP_004164 NP_659101
Location (UCSC) Chr 22:
19.71 - 19.72 Mb
Chr 16:
17.49 - 17.49 Mb
PubMed search [1] [2]

Cationic amino acid transporter 4 is a protein that in humans is encoded by the SLC7A4 gene.[1][2][3]

See also


  1. ^ Sperandeo MP, Borsani G, Incerti B, Zollo M, Rossi E, Zuffardi O, Castaldo P, Taglialatela M, Andria G, Sebastio G (Aug 1998). "The gene encoding a cationic amino acid transporter (SLC7A4) maps to the region deleted in the velocardiofacial syndrome". Genomics 49 (2): 230-6. doi:10.1006/geno.1998.5252. PMID 9598310.  
  2. ^ Hammermann R, Brunn G, Racke K (Oct 2001). "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids 21 (2): 211-9. PMID 11665818.  
  3. ^ "Entrez Gene: SLC7A4 solute carrier family 7 (cationic amino acid transporter, y+ system), member 4".  

Further reading

  • Muñoz L, Lasa A, Carricondo MT, et al. (2007). "Comparative analysis of ZAP-70 expression and Ig VH mutational status in B-cell chronic lymphocytic leukemia.". Cytometry. Part B, Clinical cytometry 72 (2): 96–102. doi:10.1002/cyto.b.20149. PMID 17051526.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome.". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMID 15461802.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Wolf S, Janzen A, Vékony N, et al. (2002). "Expression of solute carrier 7A4 (SLC7A4) in the plasma membrane is not sufficient to mediate amino acid transport activity.". Biochem. J. 364 (Pt 3): 767–75. doi:10.1042/BJ20020084. PMID 12049641.  
  • Neshat MN, Goodglick L, Lim K, Braun J (2000). "Mapping the B cell superantigen binding site for HIV-1 gp120 on a V(H)3 Ig.". Int. Immunol. 12 (3): 305–12. doi:10.1093/intimm/12.3.305. PMID 10700465.  
  • Fischer M, Küppers R (1998). "Human IgA- and IgM-secreting intestinal plasma cells carry heavily mutated VH region genes.". Eur. J. Immunol. 28 (9): 2971–7. doi:10.1002/(SICI)1521-4141(199809)28:09<2971::AID-IMMU2971>3.0.CO;2-3. PMID 9754584.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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