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Small nuclear RNA activating complex, polypeptide 1, 43kDa
Identifiers
Symbols SNAPC1; PTFgamma; SNAP43
External IDs OMIM600591 MGI1922877 HomoloGene2317 GeneCards: SNAPC1 Gene
RNA expression pattern
PBB GE SNAPC1 205443 at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 6617 75627
Ensembl ENSG00000023608 ENSMUSG00000021113
UniProt Q16533 Q8K0S9
RefSeq (mRNA) NM_003082 NM_178392
RefSeq (protein) NP_003073 NP_848479
Location (UCSC) Chr 14:
61.3 - 61.33 Mb
Chr 12:
74.88 - 74.9 Mb
PubMed search [1] [2]

snRNA-activating protein complex subunit 1 is a protein that in humans is encoded by the SNAPC1 gene.[1][2]

Interactions

SNAPC1 has been shown to interact with SNAPC4,[3] SNAPC3[4][3] and Retinoblastoma protein.[5]

References

  1. ^ Maeng JH, Yoon JB (Sep 1998). "The human PTFgamma/SNAP43 gene: structure, chromosomal location, and identification of a VNTR in 5'-UTR". J Biochem 124 (1): 23–7. PMID 9644240.  
  2. ^ "Entrez Gene: SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=6617.  
  3. ^ a b Ma, B; Hernandez N (Feb. 2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc". J. Biol. Chem. (United States) 276 (7): 5027–35. doi:10.1074/jbc.M009301200. ISSN 0021-9258. PMID 11056176.  
  4. ^ Henry, R W; Ma B, Sadowski C L, Kobayashi R, Hernandez N (Dec. 1996). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc". EMBO J. (ENGLAND) 15 (24): 7129–36. ISSN 0261-4189. PMID 9003788.  
  5. ^ Hirsch, H A; Gu L, Henry R W (Dec. 2000). "The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression". Mol. Cell. Biol. (UNITED STATES) 20 (24): 9182–91. ISSN 0270-7306. PMID 11094070.  

Further reading

  • Henry RW, Sadowski CL, Kobayashi R, Hernandez N (1995). "A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III.". Nature 374 (6523): 653–6. doi:10.1038/374653a0. PMID 7715707.  
  • Yoon JB, Roeder RG (1996). "Cloning of two proximal sequence element-binding transcription factor subunits (gamma and delta) that are required for transcription of small nuclear RNA genes by RNA polymerases II and III and interact with the TATA-binding protein.". Mol. Cell. Biol. 16 (1): 1–9. doi:10.1016/S1569-2558(08)60061-2. PMID 8524284.  
  • Henry RW, Ma B, Sadowski CL, et al. (1997). "Cloning and characterization of SNAP50, a subunit of the snRNA-activating protein complex SNAPc.". Embo J. 15 (24): 7129–36. PMID 9003788.  
  • Ma B, Hernandez N (2001). "A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc.". J. Biol. Chem. 276 (7): 5027–35. doi:10.1074/jbc.M009301200. PMID 11056176.  
  • Hirsch HA, Gu L, Henry RW (2001). "The retinoblastoma tumor suppressor protein targets distinct general transcription factors to regulate RNA polymerase III gene expression.". Mol. Cell. Biol. 20 (24): 9182–91. doi:10.1128/MCB.20.24.9182-9191.2000. PMID 11094070.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Hinkley CS, Hirsch HA, Gu L, et al. (2003). "The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition.". J. Biol. Chem. 278 (20): 18649–57. doi:10.1074/jbc.M204247200. PMID 12621023.  
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMID 15489334.  
  • Gu L, Esselman WJ, Henry RW (2005). "Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC.". J. Biol. Chem. 280 (30): 27697–704. doi:10.1074/jbc.M503206200. PMID 15955816.  
  • Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network.". Nature 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.  
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