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Sabcomeline
Systematic (IUPAC) name
(3R)-N-methoxyquinuclidine-3-carboximidoyl cyanide hydrochloride
Identifiers
CAS number 159912-58-0
ATC code none
PubChem 9577995
ChemSpider 7852359
Chemical data
Formula C10H15N3O 
Mol. mass 193.12 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease.[1] It made it to phase III clinical trials before being discontinued due to poor results.

See also

References

  1. ^ Loudon JM, Bromidge SM, Brown F, et al. (December 1997). "SB 202026: a novel muscarinic partial agonist with functional selectivity for M1 receptors". The Journal of Pharmacology and Experimental Therapeutics 283 (3): 1059–68. PMID 9399977. http://jpet.aspetjournals.org/cgi/pmidlookup?view=long&pmid=9399977. 
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