The Full Wiki

More info on Sabcomeline

Sabcomeline: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Systematic (IUPAC) name
(3R)-N-methoxyquinuclidine-3-carboximidoyl cyanide hydrochloride
CAS number 159912-58-0
ATC code none
PubChem 9577995
ChemSpider 7852359
Chemical data
Formula C10H15N3O 
Mol. mass 193.12 g/mol
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

Sabcomeline (Memric; SB-202,026) is a selective M1 receptor partial agonist that was under development for the treatment of Alzheimer's disease.[1] It made it to phase III clinical trials before being discontinued due to poor results.

See also


  1. ^ Loudon JM, Bromidge SM, Brown F, et al. (December 1997). "SB 202026: a novel muscarinic partial agonist with functional selectivity for M1 receptors". The Journal of Pharmacology and Experimental Therapeutics 283 (3): 1059–68. PMID 9399977. 


Got something to say? Make a comment.
Your name
Your email address