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Sappinia diploidea
Scientific classification
Domain: Eukaryota
Kingdom: Amoebozoa
Phylum: Flabellinea
Family: Thecamoebidae
Genus: Sappinia
Species: S. diploidea
Binomial name
Sappinia diploidea

Sappinia diploidea is a free-living[1] amoeba species.[2]

Clinical significance

It is capable of causing infectious disease in humans[3 ][4][5]

Specifically, it can cause amebic encephalitis.[6][7]


  1. ^ Visvesvara GS, Moura H, Schuster FL (June 2007). "Pathogenic and opportunistic free-living amoebae: Acanthamoeba spp., Balamuthia mandrillaris, Naegleria fowleri, and Sappinia diploidea". FEMS Immunol. Med. Microbiol. 50 (1): 1–26. doi:10.1111/j.1574-695X.2007.00232.x. PMID 17428307.  
  2. ^ Brown MW, Spiegel FW, Silberman JD (2007). "Amoeba at attention: phylogenetic affinity of Sappinia pedata". J. Eukaryot. Microbiol. 54 (6): 511–9. doi:10.1111/j.1550-7408.2007.00292.x. PMID 18070328.  
  3. ^ "Acanthamoeba: Overview - eMedicine". Retrieved 2009-01-11.  
  4. ^ Gelman BB, Rauf SJ, Nader R, et al. (May 2001). "Amoebic encephalitis due to Sappinia diploidea". JAMA 285 (19): 2450–1. PMID 11368696.  
  5. ^ Wylezich, C.; Walochnik, J.; Michel, R. (2009). "High genetic diversity of Sappinia-like strains (Amoebozoa, Thecamoebidae) revealed by SSU rRNA investigations". Parasitology research 105 (3): 869–873. doi:10.1007/s00436-009-1482-1. PMID 19495795.   edit
  6. ^ Gelman BB, Popov V, Chaljub G, et al. (October 2003). "Neuropathological and ultrastructural features of amebic encephalitis caused by Sappinia diploidea". J. Neuropathol. Exp. Neurol. 62 (10): 990–8. PMID 14575235.  
  7. ^ Marciano‐Cabral F (2009). "Free‐Living Amoebae as Agents of Human Infection". J Infect Dis 199: 1104–1106. doi:10.1086/597474.  

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