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Selective serotonin releasing agent: Wikis

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A selective serotonin releasing agent (SSRA) is a type of drug which selectively induces the release of serotonin from the pre-synaptic neuron into the synapse. This in turn leads to increased extracellular concentrations of serotonin and therefore a selective increase in serotonergic neurotransmission.

SSRAs have been used as anorectics or appetite suppressants in the past, and they have also been suggested as novel antidepressant and anxiolytic agents with a faster (immediate) onset and superior efficacy in comparison to the selective serotonin reuptake inhibitors (SSRIs).[1]

List of SSRAs

Fenfluramine, the prototypical SSRA, previously used as an anorectic before being withdrawn from the market due to toxicity concerns.
Pharmaceutical Drugs
Research Chemicals

See also


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