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Siplizumab: Wikis

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From Wikipedia, the free encyclopedia

Siplizumab ?
Monoclonal antibody
Source Human
Target CD2
Identifiers
CAS number 288392-69-8
ATC code none
PubChem  ?
Chemical data
Formula  ?
Mol. mass  ?
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Siplizumab (MEDI-507) is a novel monoclonal antibody with a human IgG1, kappa directed to CD2. The agent has shown potent immunomodulatory effects, selectively suppressing the function of T and NK cells, and is currently being tested as a possible treatment for psoriasis and in the prevention of graft-versus-host disease.[1]

References

  1. ^ ClinicalTrials.gov
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