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Sparteine: Wikis


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Systematic (IUPAC) name
CAS number 90-39-1
ATC code C01BA04
PubChem 7014
Chemical data
Formula C 15H26N2  
Mol. mass 234.380 g/mol
Synonyms (6R,8S,10R,12S)- 7,15-diazatetracyclo [,7.010,15] heptadecane
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Sparteine is a class 1a antiarrhythmic agent; a sodium channel blocker. It is an alkaloid and can be extracted from scotch broom. It is the predominant alkaloid in Lupinus mutabilis, and is thought to chelate the bivalents calcium and magnesium. It is not FDA approved for human use as an antiarrhythmic agent, and it is not included in the Vaughn-Williams class of antiarrhythmic drugs.

It is also used as a chiral base in organic chemistry, and as a ligand in organic synthesis.



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