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Sulfadimidine
Systematic (IUPAC) name
4-amino-N-(4,6-dimethylpyrimidin-2-yl)
benzenesulfonamide
Identifiers
CAS number 57-68-1
ATC code J01EB03 QJ01EQ03 QP51AG01
PubChem 5327
Chemical data
Formula C12H14N4O2S 
Mol. mass 278.33 g/mol
Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Sulfadimidine or sulfamethazine,[1] is a sulfonamide antibacterial.

There are non-standardizeda abbreviations for it as "sulfadimidine" (abbreviated SDI[2][3] and more commonly but less reliablyb SDD[4][5]) and as "sulfamethazine" (abbreviated SMT[6][7] and more commonly but less reliablyc SMZ[8][9]). Other names include sulfadimerazine, sulfadimezine, and sulphadimethylpyrimidine.[1]

Notes

  • ^a  Abbreviations are not found in the databases (such as ChemDB, ChemIDplus, PubChem), but often seen in the published literature.[citation needed]
  • ^b  "SDD" is not found in databases, but often seen in the published literature; it could however be confused with Tiferron/Sodium catechol sulfate (1,2-Dihydroxybenzene-3,5-disulfonic acid disodium Salt), uncommon but found officially abbreviated SDD in the ChemIDplus database.[10]
  • ^c  "SMZ" is not found in databases, but often seen in the published literature; it could however be confused with sulfamethoxazole, also seen abbreviated SMZ.[citation needed]

References

  1. ^ a b "Sulfadimidine" (in French). Banque de données automatisée sur les médicaments. 15 November 1999. http://www.biam2.org/www/Sub3321.html. Retrieved 14 September 2009. 
  2. ^ Romváry, A; Simon (1992). "Sulfonamide residues in eggs". Acta veterinaria Hungarica 40 (1-2): 99–106. ISSN 0236-6290. PMID 1476095. 
  3. ^ Reddy; Jain, S. K.; Uppal, R. P. (1988). "Pharmacokinetic studies of sulphonamides in poultry". Indian Journal of Animal Sciences. http://www.cababstractsplus.org/abstracts/Abstract.aspx?AcNo=19892292426. 
  4. ^ Kamakura, K; Hasegawa; Koiguchi; Miyata; Okamoto; Narita; Hirahara; Yamana et al. (1993). "Studies on the identification of sulfadimidine in pork by high performance liquid chromatography with photodiode array detector and gas chromatograph-mass spectrometry". Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences (111): 61–5. ISSN 0077-4715. PMID 7920569. 
  5. ^ Garg, SK; Ghosh; Mathur (Jan 1986). "Comparative pharmacokinetic study of four different sulfonamides in combination with trimethoprim in human volunteers". International journal of clinical pharmacology, therapy, and toxicology 24 (1): 23–5. ISSN 0174-4879. PMID 3485584. 
  6. ^ Peña, MS; Salinas; Mahedero; Aaron (Feb 1994). "Solvent effect on the determination of sulfamethazine by room-temperature photochemically induced fluorescence". Talanta 41 (2): 233–6. doi:10.1016/0039-9140(94)80113-4. ISSN 0039-9140. PMID 18965913. 
  7. ^ Kaniou, S; Pitarakis; Barlagianni; Poulios (Jul 2005). "Photocatalytic oxidation of sulfamethazine". Chemosphere 60 (3): 372–80. doi:10.1016/j.chemosphere.2004.11.069. ISSN 0045-6535. PMID 15924956. 
  8. ^ Calvo, R; Sarabia; Carlos; Du Souich (Mar 1987). "Sulfamethazine absorption and disposition: effect of surgical procedures for gastroduodenal ulcers". Biopharmaceutics & drug disposition 8 (2): 115–24. doi:10.1002/bdd.2510080203. ISSN 0142-2782. PMID 3593892. 
  9. ^ De Liguoro, M; Fioretto; Poltronieri; Gallina (Jun 2009). "The toxicity of sulfamethazine to Daphnia magna and its additivity to other veterinary sulfonamides and trimethoprim". Chemosphere 75 (11): 1519–24. doi:10.1016/j.chemosphere.2009.02.002. ISSN 0045-6535. PMID 19269673. 
  10. ^ http://chem.sis.nlm.nih.gov/chemidplus/ProxyServlet?objectHandle=Search&actionHandle=getAll3DMViewFiles&nextPage=jsp%2Fcommon%2FChemFull.jsp%3FcalledFrom%3Dlite&chemid=000149451&formatType=_3D

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