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Taste receptor, type 2, member 10
Symbols TAS2R10; TRB2; MGC126811; MGC126813; T2R10
External IDs OMIM604791 MGI2681207 HomoloGene41540 GeneCards: TAS2R10 Gene
RNA expression pattern
PBB GE TAS2R10 221397 at tn.png
More reference expression data
Species Human Mouse
Entrez 50839 387342
Ensembl ENSG00000121318 ENSMUSG00000053389
UniProt Q9NYW0 Q7M725
RefSeq (mRNA) NM_023921 NM_199154
RefSeq (protein) NP_076410 NP_954605
Location (UCSC) Chr 12:
10.87 - 10.87 Mb
Chr 6:
131.62 - 131.63 Mb
PubMed search [1] [2]

Taste receptor type 2 member 10 is a protein that in humans is encoded by the TAS2R10 gene.[1][2][3]

This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.[3]

See also


  1. ^ Adler E, Hoon MA, Mueller KL, Chandrashekar J, Ryba NJ, Zuker CS (Apr 2000). "A novel family of mammalian taste receptors". Cell 100 (6): 693-702. PMID 10761934.  
  2. ^ Matsunami H, Montmayeur JP, Buck LB (Apr 2000). "A family of candidate taste receptors in human and mouse". Nature 404 (6778): 601-4. doi:10.1038/35007072. PMID 10766242.  
  3. ^ a b "Entrez Gene: TAS2R10 taste receptor, type 2, member 10".  

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.



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