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Taste receptor, type 2, member 46
Identifiers
Symbols TAS2R46; MGC134865; T2R46; T2R54
External IDs MGI2681256 HomoloGene77601 GeneCards: TAS2R46 Gene
Orthologs
Species Human Mouse
Entrez 259292 387348
Ensembl n/a ENSMUSG00000059382
UniProt n/a Q7M721
RefSeq (mRNA) NM_176887 NM_207023
RefSeq (protein) NP_795368 NP_996906
Location (UCSC) n/a Chr 6:
132.62 - 132.62 Mb
PubMed search [1] [2]

Taste receptor type 2 member 46 is a protein that in humans is encoded by the TAS2R46 gene.[1][2]

References

  1. ^ Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet 32 (3): 397-401. doi:10.1038/ng1014. PMID 12379855.  
  2. ^ "Entrez Gene: TAS2R46 taste receptor, type 2, member 46". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=259292.  

Further reading

  • Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction.". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.  
  • Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste.". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.  
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMID 12477932.  
  • Zhang Y, Hoon MA, Chandrashekar J, et al. (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways.". Cell 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.  
  • Conte C, Ebeling M, Marcuz A, et al. (2003). "Identification and characterization of human taste receptor genes belonging to the TAS2R family.". Cytogenet. Genome Res. 98 (1): 45–53. doi:10.1159/000068546. PMID 12584440.  
  • Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes.". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.  
  • Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates.". Genetics 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMID 15744053.  

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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