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TC-5619: Wikis

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TC-5619
Systematic (IUPAC) name
N-[(2S,3S)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]oct-3-yl]-1-benzofuran-2-carboxamide
Identifiers
ATC code  ?
PubChem 16727410
Chemical data
Formula C22H23N3O2 
Mol. mass 361.437
SMILES eMolecules & PubChem
Therapeutic considerations
Pregnancy cat.  ?
Legal status

TC-5619 is a drug developed by Targacept which acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and is currently being developed through a collaboration between Targacept and AstraZeneca as a potential treatment for schizophrenia.[1] Phase I clinical trials have been completed successfully and it is currently in Phase II trials.[2]

References

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