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Transferrin receptor (p90, CD71)

PDB rendering based on 1cx8.
Available structures
1cx8, 1de4, 1suv, 2nsu
Symbols TFRC; CD71; TFR; TFR1; TRFR
External IDs OMIM190010 MGI98822 HomoloGene2429 GeneCards: TFRC Gene
RNA expression pattern
PBB GE TFRC 208691 at tn.png
PBB GE TFRC 207332 s at tn.png
More reference expression data
Species Human Mouse
Entrez 7037 22042
Ensembl ENSG00000072274 ENSMUSG00000022797
UniProt P02786 Q542D9
RefSeq (mRNA) NM_003234 NM_011638
RefSeq (protein) NP_003225 NP_035768
Location (UCSC) Chr 3:
197.26 - 197.29 Mb
Chr 16:
32.53 - 32.55 Mb
PubMed search [1] [2]

Transferrin receptor (p90, CD71), (Cluster of Differentiation 71) also known as TFRC, is a human gene.



TFRC has been shown to interact with GABARAP[1] and HFE.[2][3]

See also

Further reading


  1. ^ Green, Frank; O'Hare Thomas, Blackwell Aaron, Enns Caroline A (May. 2002). "Association of human transferrin receptor with GABARAP". FEBS Lett. (Netherlands) 518 (1-3): 101–6. ISSN 0014-5793. PMID 11997026.  
  2. ^ Feder, J N; Penny D M, Irrinki A, Lee V K, Lebrón J A, Watson N, Tsuchihashi Z, Sigal E, Bjorkman P J, Schatzman R C (Feb. 1998). "The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding". Proc. Natl. Acad. Sci. U.S.A. (UNITED STATES) 95 (4): 1472–7. ISSN 0027-8424. PMID 9465039.  
  3. ^ West, A P; Bennett M J, Sellers V M, Andrews N C, Enns C A, Bjorkman P J (Dec. 2000). "Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE". J. Biol. Chem. (UNITED STATES) 275 (49): 38135–8. doi:10.1074/jbc.C000664200. ISSN 0021-9258. PMID 11027676.  


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