The Full Wiki

More info on Tacalcitol

Tacalcitol: Wikis

Advertisements

Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.

Encyclopedia

From Wikipedia, the free encyclopedia

Tacalcitol
Systematic (IUPAC) name
(1S,3R,5Z,7E,24 R)-9,10-secocholesta-5,7,10-triene-1,3,24-triol
Identifiers
CAS number 57333-96-7
ATC code D05AX04
PubChem 5283734
Chemical data
Formula C 27H44O3  
Mol. mass 416.64
Synonyms (1R,3S,5Z)-5-[(2E)-2-[(1 R,3aS,7aR)-1-[(2R,5R)-5-hydroxy-6-methylheptan-2-yl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1 H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexane-1,3-diol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Topical

Tacalcitol is a synthetic vitamin D3 analogue.[1]

Tacalcitol is marketed under several names, including Curatoderm and Bonalfa.

Mechanism

Tacalcitol exerts its biological activity by preventing the proliferation of keratinocytes.

Uses

It is used to treat psoriasis.

It has been used for vitiligo[2] and Hailey-Hailey disease.[3]

References

Advertisements

Advertisements






Got something to say? Make a comment.
Your name
Your email address
Message