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Tafluprost
Systematic (IUPAC) name
isopropyl (5Z)-7-{(1R,2R,3R,5S)-2-[(1 E)-3,3-difluoro-4-phenoxybut-1-en-1-yl]-3,5-dihydroxycyclopentyl}hept-5-enoate
Identifiers
CAS number 209860-87-7
ATC code S01EE05
PubChem 6433101
Chemical data
Formula C 25H34F2O5  
Mol. mass 452.531266 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes Topical (eye drops)

Tafluprost (trade name Taflotan, marketed by Santen Pharmaceutical Co.) is a prostaglandin analogue used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.[1][2]

Taflotan contains 15 µg/ml Tafluprost. Taflotan sine is a preservative-free, single-dose formulation containing 0.3 ml per dose.[3]

References

  1. ^ Schubert-Zsilavecz, M, Wurglics, M, Neue Arzneimittel 2008/2009
  2. ^ Santen Home Page
  3. ^ Gelbe Liste (in German)
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