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Talaporfin: Wikis


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Systematic (IUPAC) name
N-{[(2S,3S)-7-carboxy-3-(2-carboxyethyl)-12-ethyl-2,8,13,18-tetramethyl-17-vinyl-2,3-dihydroporphyrin-5-yl]acetyl}- L-aspartic acid
CAS number 110230-98-3
220201-34-3 (sodium salt)
ATC code none
PubChem 5486799
Chemical data
Formula C 38H41N5O9  
Mol. mass 711.76 g/mol
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Prescription only
Routes IV

Talaporfin (INN, also known as aspartyl chlorin, mono-L-aspartyl chlorine e6, NPe6, or LS11) is a photosensitizer used in photodynamic therapy (PDT).

It absorbs red light at 664nm normally provided by a laser tuned to this wavelength.[1]

It was approved in Japan (in 2004) for PDT of lung cancer and marketed as Laserphyrin.[2]


  1. ^ "Photodynamic Therapy (PDT) for Lung Cancers" 2006
  2. ^ "Photodynamic therapy using Laserphyrin for centrally located early stage lung cancer" 2006


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