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Tazobactam: Wikis


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Systematic (IUPAC) name
(2S,3S,5R)-3-methyl-7-oxo-3-(1 H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide
CAS number 89786-04-9
ATC code J01CG02
PubChem  ?
DrugBank EXPT03012
Chemical data
Formula C 10H12N4O5S 
Mol. mass 300.289 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
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Therapeutic considerations
Pregnancy cat.  ?
Legal status
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Tazobactam is a compound which inhibits the action of bacterial beta-lactamases. It is added to the extended spectrum beta-lactam antibiotic piperacillin to produce Tazocin or Zosyn or Piprataz (manufactured by Gepach International). It broadens the spectrum of piperacillin by making it effective against organisms that express beta-lactamase and would normally degrade piperacillin.

Tazobactam sodium is a derivative of the penicillin nucleus and is a penicillanic acid sulfone.

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