The City of London Migraine Clinic: Wikis


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The City of London Migraine Clinic
Logo full.png
Established 1980
Type Research and outpatient centre
Director of clinical research Dr Anne MacGregor
Consultant neurologist Dr J N Blau MD FRCP FRCPath
Chief executive Ms Heather Sim
Location 22 Charterhouse Square
Staff more than 10
Publication Open Door
Website The City of London Migraine Clinic

The City of London Migraine Clinic is a research centre and outpatient service for people with migraine and other primary headaches. It has more than 29 years of experience in solving headaches. They have a team of registered doctors with a special interest in headaches providing specialist care in a charitable setting. It is a registered charity and social enterprise and is independent of the NHS. In 2009 around 2,500 patients were seen at the Clinic. Patients are seen by GP referral and self referral. Most patients live in London and the Home Counties but patients come from other parts of the UK and abroad.



Dr Marcia Wilkinson founded the Clinic with Dr Nat Blau in 1980 as an independent registered medical charity affiliated with St Bartholomew's Hospital and became patron on her retirement in 1997. She has a long standing interest in migraine and is widely published in the subject. Wilkinson won the first Elizabeth Garrett Anderson Award, presented at the Headache World 2000 meeting in London.


Map showing the Location of the City of London Migraine Clinic

The Clinic is in a townhouse on Charterhouse Square at the edge of the City of London, where it has been since 1980.

22 Charterhouse Square, London, EC1M 6DX

Phone number: 020 7251 3322




The clinic is an active research centre with specific interests in migraine and cluster headaches. New drug and non-drug treatments are tested in clinical trials enabling patients to participate; there is also comparative research into established treatments. All participation is voluntary - whether or not patients choose to take part does not affect their care in the clinic in any way.

Outpatient Clinic

The only independent, charitable clinic in the UK that is entirely focused on headaches and migraines. With unparalleled experience in helping people (including children) suffering from migraines, cluster headaches and other types of headaches. The clinic is the leading centre of knowledge about hormonally-related headaches and migraine.

Appointments can be made on the website or by phone.


The City of London Migraine Clinic does not receive NHS funding, and are continually trying to raise funds for the Clinic. [Click here] for an illustration why making a contribution is important and why finding funds for migraine research and treatment is difficult. The annual running costs amount to over £265,000, even though two of the Clinic’s doctors give their services free. The Clinic was extremely grateful to our patients and other supporters for their generous donations which exceeded £130,000 in the 15 months to 31 March 2008.

The City of London Migraine Clinic receive an annual grant from the Migraine Action Association, who also support some of our research projects. We conduct clinical trials sponsored by pharmaceutical companies and also undertake independent research, returning all income to the Clinic, which is a registered medical charity. We receive donations from commercial organisations, trusts and other donors. In addition we raise money by appeals and have a street collection on Alexandra Rose Day. However, there is still a considerable annual shortfall.

The Clinic has now started raising funds when supporters shopping online using and supporters searching online using

Annual campaign during National Migraine Week.

Fact sheets

The Front of The City of London Migraine Clinic


  • In 2008 Alison Frith, Clinical Research Sister at the City of London Migraine Clinic, was voted the Best Healthcare Professional 2008.
  • In 2002 Dr. Anne MacGregor, was awarded the Elizabeth Garret Anderson Award.
  • In 2000 Dr. Marcia Wilkinson, was awarded the Elizabeth Garret Anderson Award

External links

Video clips


Books for the medical profession and the public

  • Frith Alison. Coping with Headaches and Migraine. Sheldon Press 2009 ISBN 9781847090386
  • MacGregor EA, Frith A (Eds). ABC of Headache. Wiley Blackwell 2009 ISBN 9781405170666
  • MacGregor EA, Jensen R (Eds). Migraine and Other Primary Headaches (Oxford Pain Management Library). OUP 2008 ISBN 0199545146
  • MacGregor Dr Anne. Understanding Migraine and Other Headaches. Family Doctor Publications (BMA) Updated 2006 ISBN 1 903474 49 3
  • MacGregor Dr. Anne. Understanding the menopause and HRT. Family Doctor Publications (BMA). Updated 2006 ISBN 1 903474 24 8
  • Peccarisi C, MacGregor A. Mal di testa, addio! Sperling & Kupfer 2006 ISBN 88-6061-004-4
  • MacGregor Dr. Anne. Is HRT right for you? Sheldon Press 3rd Edition 2003
  • MacGregor Dr Anne. Migraine in Women. Martin Dunitz Revised Edition 2003 ISBN 1-85317-744-X

Peer reviewed journals

  • MacGregor EA. Headache and Hormone Replacement Therapy in the Postmenopausal Woman. Current Treatment Options in Neurology 2009; 11:10–17
  • MacGregor EA. Perimenstrual headaches: unmet needs. Curr Pain Headache Rep. 2008 Dec;12(6):468-74.
  • MacGregor A. Oral contraception: types, suitability and considerations. Prescriber 2008; 19 (15/16): 17-34.
  • MacGregor EA. Estrogen and Migraine: Correlations and Prevention. Headache 2008; 48: S99-S107.
  • MacGregor A. Prescribing oral contraception. Prescriber 2008;19(7):44,46.
  • MacGregor EA. Menstrual Migraine. Current Opinion in Neurology 2008; 21(3): 309-15
  • Elkind AH, MacGregor EA. Frovatriptan for the acute treatment of migraine and prevention of predictable menstrual migraine. Expert Rev. Neurotherapeutics 2008: 8(4): 553–566
  • MacGregor EA. Migraine, the menopause and hormone replacement therapy: a clinical review. J Fam Plann Reprod Health Care 2007; 33(4): 245–249
  • MacGregor EA. Migraine and use of combined hormonal contraceptives: a clinical review. J Fam Plann Reprod Health Care 2007; 33(3): 159-169
  • MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care 2007; 33(2): 83–93
  • MacGregor EA. Menstrual Migraine: a clinical review. J Fam Plann Reprod Health Care 2007; 33(1): 36–47
  • MacGregor EA. NICE guidance on LARC. J Fam Plann Reprod Health Care 2006;32(1):52.
  • MacGregor EA, Frith A, Ellis J, Aspinall L, Hackshaw A. Incidence of migraine relative to menstrual cycle phases of rising and falling estrogen. Neurology 2006;67(12):2154-8.
  • MacGregor EA, Frith A, Ellis J, Aspinall L, Hackshaw A. Prevention of menstrual attacks of migraine: a double-blind placebo-controlled crossover study. Neurology 2006;67(12):2159-63.
  • MacGregor EA. Migraine and the Menopause. J Brit Menopause Soc 2006;12(3):104-8
  • Thorne SA, MacGregor EA, Nelson-Piercy C, Risks of contraception & pregnancy in heart disease. Heart 2006;92: 1520-1525
  • MacGregor A. Combined and progestogen-only contraception. Prescriber 2006;17:52-61
  • Thorne S, Nelson-Piercy C, MacGregor A, Gibbs S, Crowhurst J, Panay N, Rosenthal E, Walker F, Williams D, de Swiet M, Guillebaud J. Pregnancy and contraception in heart disease and pulmonary arterial hypertension. J Fam Plann Reprod Health Care 2006; 32(2): 75–81
  • Blau JN. Feeling and seeing headaches. J Headache & Pain 2005; 6: 10-19.
  • Blau JN. Medical acronyms (Letter) J R Soc Med 2005;98: 45.
  • Blau JN. Water deprivation: a new migraine precipitant. Headache 2005; 45: 757-759.
  • MacGregor EA. Clinical aspects of premenstrual headache. Current Headache Reports 2005; 4(6):191-195
  • MacGregor EA. Female hormones and migraine. Rev Neurol (Paris) 2005;161:1-2.
  • MacGregor EA, Frith A, Ellis J, Apsinall L. Predicting menstrual migraine with a home-use fertility monitor. Neurology 2005;64:561-3.
  • MacGregor EA, Mishell Jr DR. Relation of Headache to Method of Contraception. Dialogues in Contraception 2005;9(3):5-7
  • MacGregor A. Diagnosing Migraine Aura. The Female Patient 2005;30: 45-50 (AMA/CME Test: pp51–52)
  • MacGregor EA, Clark B. Combined oral contraceptives and migraine: is there an increased risk of ischemic stroke? The Female Patient 2005;30(4):50-56.
  • Blau JN, Kell CA, Sperling JM. Water deprivation headache: A new headache with 2 variants. Headache 2004;44:79-83.
  • Blau JN. Harold G Wolff: The man and his migraine. Cephalalgia 2004;24:215-222.
  • Blau JN, Engel HO. Individualizing treatment with Verapamil for cluster headache patients. Headache 2004;44:1013-1018.
  • Blau JN. Migraine auras: facts and questions. Headache & pain 2004;15:59-64.
  • Blau JN. Pony-tail headache: A pure extracranial headache. Headache 2004;44:411-413.
  • MacGregor EA. A practical guide to menstrual migraine. Headache in Practice 2004; 1(2):8-10
  • MacGregor EA. How to manage migraine during pregnancy. Headache in Practice 2004; 1(3):1-4
  • MacGregor EA. Sumatriptan taken during the mild pain phase was more effective than Placebo for relief of menstrual migraine. Evidence-based Obstetrics & Gynecology 2004;6(3):139-140.
  • MacGregor EA. Oestrogen and attacks of migraine with and without aura. Lancet Neurol 2004;3:354-61.
  • MacGregor EA, Brandes J, Gendolla A, Giammarco R. Migraine treatment strategies: the global Migraine And Zolmitriptan Evaluation (MAZE) survey – Phase IV. Curr Med Res Opin 2004;20(11):1777-83.
  • MacGregor EA, Hackshaw A. Prevalence of migraine on each day of the natural menstrual cycle. Neurology 2004;63:351-3.
  • MacGregor EA, Brandes J, Eikermann A, Giammarco R. Impact of migraine and patients and their families: the Migraine And Zolmitriptan Evaluation (MAZE) survey – Phase III. Curr Med Res Opin 2004;20(7):1143-50.
  • Cohen SI, Blau JN. Lifelong migraine aura without headache: change of pattern with upper respiratory infection. J R Soc Med 2003; 96: 504-505.
  • MacGregor EA. Q&A on oral contraceptives. Recent Advances in Reproductive Medicine 2003;16:7.
  • MacGregor EA. Is there any good evidence to support limiting the duration of the prescribing of Dianette? Pulse 2003;
  • MacGregor EA. Oral contraception: the benefits and risks. Prescriber 2003;14:59-68
  • Steiner TJ, Diener H-C, MacGregor EA, Schoenen J, Muirhead N, Sikes CR. Comparative efficacy of eletriptan and zolmitriptan in the acute treatment of migraine. Cephalalgia 2003;23:942-952.
  • Garcia-Ramos G, MacGregor EA, Hilliard B, Bordini CA, Leston J, Hettiarachchi J. Comparative efficacy of eletriptan vs. naratriptan in the acute treatment of migraine. Cephalalgia 2003;23:869-876.
  • Boardman HF, Thomas E, Millson DS, MacGregor EA, Laughey WF, Croft PR. North Staffordshire Headache Survey: development, reliability and validity of a questionnaire for use in a general population survey. Cephalalgia 2003;23:325-331.
  • MacGregor EA, Brandes J, Eikermann A. Migraine prevalence and treatment patterns: results of the global migraine and zolmitriptan evaluations (MAZE) survey. Headache 2003;23.

Chapters in books and other publications

  • MacGregor EA. Migraine in women. In: Kernick D, Goadsby P. Headache: A Practical Care Manual. Oxford, Oxford University Press 2008
  • MacGregor EA. Pharmacotherapy. In: Hutchinson S, Peterlin BL. Menstrual Migraine. Oxford American Pain Library. Oxford, Oxford University Press 2008: 45-49
  • MacGregor EA. Acute Migraine Attacks. In: Candelise L, Hughes R, Liberati A, Uitdehaag B, Warlow C. Management of Neurological Disorders: an evidence-based approach. Oxford, Blackwell Publishing, 2007: 29-39
  • Steiner T.J. MacGregor E.A., Davies P. Guidelines for All Healthcare Professionals in the Diagnosis and Management of Migraine and Tension-Type, Cluster and Medication-Overuse Headache. British Association for the Study of Headache 2007.
  • Blau JN. How do so many different triggers provoke similar migraine attacks? In Headache and Migraine 9.Sorbi MJ, Couturier EGM, & Mérelle SYM (Eds.) Utrecht: Anglo Dutch Migraine Association, 2006. 185-196
  • JN Blau In: Development of Physics Applied to Medicine in the UK 1945-1990 The transcript of a Witness Seminar held by the Wellcome Trust Centre for the History of Medicine at UCL, London, on 5 July 2005 Eds DA Christie, Tansey EM Volume 28 2006: 72-73
  • Massiou H, MacGregor EA. Influence of female hormones on migraine. In: Olesen J, Tfelt-Hansen P, Welch KMA.The Headaches (Third Edition) Philadelphia, Lippincott Williams & Wilkins, 2006: 331-342
  • MacGregor EA. Menstrual Migraine. In: Rees M, Ravnikar V, Hope S (eds). The abnormal menstrual cycle. Taylor & Francis, 2005:197-218.
  • MacGregor EA. The woman with monthly headaches. In: Purdy RA, Rapoport AM, Sheftell FD, Tepper SJ (eds). Advanced Therapy of Headache (Second Edition). Hamilton, BC Decker Inc, 2005; 31-37
  • MacGregor EA. Menstrual Migraine. In: Rees M, Ravnikar V, Hope S (eds). The abnormal menstrual cycle. Taylor & Francis 2005:197-218.
  • MacGregor EA. The woman with monthly headaches. In: Purdy RA, Rapoport AM, Sheftell FD, Tepper SJ (eds). Advanced Therapy of Headache (Second Edition). Hamilton, BC Decker Inc, 2005; 31-37
  • Blau JN. Possible benefits of migraine aura: A discussion paper. In: Headache and migraine. Couturier EGM, Sorbi MJ, Verspin ECB. Utrecht, Anglo-Dutch Migraine Association 2004:55-59.
  • Blau JN. Tension-type headache – nature and characteristics. A personal view. In: Proceedings 7th Congress of European Society Clinical Neuropharmacology. Battisini L (ed). Bologna, Medimond 2004: 155-162. Paper given in Trieste, Italy, 5-9 May 2004.
  • Loder EW, MacGregor EA. Menstrual Migraine. In: Loder EW, Marcus D. Migraine in Women. Hamilton, BC Decker Inc 2004;102-111
  • Blau JN, Merskey H. Cervicogenic headache: a critical view. In Cervicogenic Headache. Basic Concepts. Sjaastad O, Fredriksen TA, Bono G, Nappi G eds. London, Smith-Gordon 2003: 125-129.
  • Blau JN. Merskey H. Cervicogenic headache: A critical view. In: Cervicogenic headache. Basicconcepts. Sjaastad O, Fredriksen TA, Bono G, Nappi G, eds. London, Smith-Gordon 2003; 125-129.
  • Chauvet S, MacGregor EA. MIDAS as a tool for monitoring the benefits of treatment strategies over time. In: Olesen J, Steiner TJ, Liptons RB (eds) Frontiers in Headache Research Vol 11. Reducing the Burden of Headache. Oxford University Press 2003: 67-71.

Coordinates: 51°31′14″N 0°06′01″W / 51.5205268564751°N 0.10041385889053°W / 51.5205268564751; -0.10041385889053345


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