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Thiethylperazine
Systematic (IUPAC) name
2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10 H-phenothiazine
Identifiers
CAS number 1420-55-9
ATC code R06AD03
PubChem 5440
DrugBank APRD00323
Chemical data
Formula C 22H29N3S2  
Mol. mass 399.618 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 60%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Thiethylperazine is a piperazine phenothiazine. It is approved for treating of nausea and vomiting.

References

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Thiethylperazine
File:Thiethylperazine
Systematic (IUPAC) name
2-(ethylthio)-10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
Identifiers
CAS number 1420-55-9
ATC code R06AD03
PubChem CID 5440
DrugBank APRD00323
Chemical data
Formula C22H29N3S2 
Mol. mass 399.618 g/mol
Pharmacokinetic data
Protein binding 60%
Therapeutic considerations
Pregnancy cat.  ?
Legal status
 Y(what is this?)  (verify)

Thiethylperazine (Torecan) is an antiemetic of the phenothiazine class. Though it was never licensed or used as an antipsychotic, it may have such effects.

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Bourquin, J. P.; Schwarb, G.; Gamboni, G.; Rischer, R.; Ruesch, L.; Uldimann, S. G.; Theuss, U.; Schenke, E.; Renz, J.; Helv. Chim. Acta 1958, 41, 1072.

References


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