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Thiofentanyl
Systematic (IUPAC) name
N-phenyl-N-{1-[2-(2-thienyl)ethyl]piperidin-4-yl}propanamide
Identifiers
CAS number 60771-38-2
ATC code none
PubChem 62380
Chemical data
Formula C 20H26N2OS 
Mol. mass 342.499 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status Schedule I (CA) Class A (UK) Schedule I (US)
Routes  ?

Thiofentanyl is an opioid analgesic that is an analogue of fentanyl.

Thiofentanyl was sold briefly on the black market in the early 1980s, before the introduction of the Federal Analog Act which for the first time attempted to control entire families of drugs based on their structural similarity rather than scheduling each drug individually as they appeared. [1] Thiofentanyl is made with the same synthetic route as fentanyl, but by substituting 2-(2-bromoethyl)thiophene for phenethyl bromide in the synthesis.

Thiofentanyl has similar effects to fentanyl. Side effects of fentanyl analogues are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression which can be life-threatening.

References

  1. ^ Henderson GL. Designer Drugs: Past History and Future Prospects. Journal of Forensic Sciences 1988; 33(2):569-575







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