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Thrombocytes are cells that play a key role in blood clotting. In mammals, thrombocytes are anucleated cell fragments called platelets. Nucleated thrombocytes of nonmammalian vertebrates differ from the mammalian thrombocytes not only in having a nucleus and thus resembling B lymphocytes, but also these nucleated thrombocytes do not aggregate in response to ADP, serotonin and adrenaline (they do aggregate with thrombin, of course).[1]

References

  1. ^ Nature 220, 509 - 510 (02 November 1968); doi:10.1038/220509a0 ADP is not Involved in Thrombin-Induced Aggregation of Thrombocytes of a Non-mammalian Vertebrate FRANK A. BELAMARICH, DAVID SHEPRO & MARJA KIEN Biology Department, Boston University, Massachusetts. [1]
  • Meseguer J, Esteban MA, Rodríguez A. 2002. Microscopy Research and Technique. The Biology of Phagocytosis, Volume 57, Issue 6 , Pages 491 - 497.

Thrombocytes are cells that play a key role in blood clotting. In mammals, thrombocytes are anucleated cell fragments called platelets. Nucleated thrombocytes of nonmammalian vertebrates differ from the mammalian thrombocytes not only in having a nucleus and thus resembling B lymphocytes, but also these nucleated thrombocytes do not aggregate in response to ADP, serotonin and adrenaline (they do aggregate with thrombin, of course).

Being not complete cells, thrombocytes do not have major organelles except for asctin and myosin.

Platelet formation: 1. Repeated mitosis with no cytokinesis results in megakaryotes. 2. Granules are developed. 3. Pushes against sinusoid and sends cytoplasmic extensions into bloodstream. 4. Extensions break off into small granules. 5. Granules contain chemicals used in clotting.

[1]

References

  1. ^ Nature 220, 509 - 510 (02 November 1968); doi:10.1038/220509a0 ADP is not Involved in Thrombin-Induced Aggregation of Thrombocytes of a Non-mammalian Vertebrate FRANK A. BELAMARICH, DAVID SHEPRO & MARJA KIEN Biology Department, Boston University, Massachusetts. [1]
  • Meseguer J, Esteban MA, Rodríguez A. 2002. Microscopy Research and Technique. The Biology of Phagocytosis, Volume 57, Issue 6 , Pages 491 - 497.

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