| Thyroid adenoma | |
|---|---|
| Classification and external resources | |
| ICD-9 | 226 |
| DiseasesDB | 13071 |
| MeSH | D013964 |
A thyroid adenoma is a benign tumor of the thyroid gland.
Almost all thyroid adenomas are follicular adenomas.[1] Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.[2] There are no papillary thyroid adenomas.[2]
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A thyroid adenoma is distinguished from a multinodular goiter of the thyroid in that an adenoma is typically solitary, and is a neoplasm resulting from a genetic mutation (or other genetic abnormality) in a single precursor cell.[3] In contrast, a multinodular goiter is usually thought to result from a hyperplastic response of the entire thyroid gland to a stimulus, such as iodine deficiency.
Careful pathological examination may be necessary to distinguish a thyroid adenoma from a minimally invasive follicular thyroid carcinoma.[3]
A thyroid adenoma may be clinically silent ("cold" or "warm" adenoma), or it may be a functional tumor, producing excessive thyroid hormone ("hot" adenoma). In this case, it may result in symptomatic hyperthyroidism, and may be referred to as a toxic thyroid adenoma.
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