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Thyroid adenoma
Classification and external resources
ICD-9 226
DiseasesDB 13071
MeSH D013964

A thyroid adenoma is a benign tumor of the thyroid gland.

Almost all thyroid adenomas are follicular adenomas.[1] Follicular adenomas can be described as "cold", "warm" or "hot" depending on their level of function.[2] There are no papillary thyroid adenomas.[2]

Contents

Differential diagnosis

A thyroid adenoma is distinguished from a multinodular goiter of the thyroid in that an adenoma is typically solitary, and is a neoplasm resulting from a genetic mutation (or other genetic abnormality) in a single precursor cell.[3] In contrast, a multinodular goiter is usually thought to result from a hyperplastic response of the entire thyroid gland to a stimulus, such as iodine deficiency.

Careful pathological examination may be necessary to distinguish a thyroid adenoma from a minimally invasive follicular thyroid carcinoma.[3]

Presentation

A thyroid adenoma may be clinically silent ("cold" or "warm" adenoma), or it may be a functional tumor, producing excessive thyroid hormone ("hot" adenoma). In this case, it may result in symptomatic hyperthyroidism, and may be referred to as a toxic thyroid adenoma.

References

  1. ^ Cotran, Ramzi S.; Kumar, Vinay; Fausto, Nelson; Nelso Fausto; Robbins, Stanley L.; Abbas, Abul K. (2005). Robbins and Cotran pathologic basis of disease. St. Louis, Mo: Elsevier Saunders. pp. 1117. ISBN 0-7216-0187-1.  
  2. ^ a b "Endocrine Pathology". http://library.med.utah.edu/WebPath/ENDOHTML/ENDO037.html. Retrieved 2009-05-08.  
  3. ^ a b Ramzi Cotran, Vinay Kumar, Tucker Collins (1999). Robbins Pathologic Basis of Disease, 6th Edition. W.B. Saunders. ISBN 072167335X.  

See also








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