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Tosufloxacin: Wikis

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Tosufloxacin
Systematic (IUPAC) name
7-(3-Aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid
Identifiers
CAS number 100490-36-6
ATC code none
PubChem 5517
Chemical data
Formula C 19H15F3N4O3  
Mol. mass 404.34 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.  ?
Legal status
Routes  ?

Tosufloxacin is a fluoroquinolone antibiotic. It has a controversial safety profile in relation to other fluoroquinolones. It is associated with severe thrombocytopenia and nephritis, and hepatotoxicity.[1] It is sold in Japan under the brand name Ozex.

See also

References

  1. ^ Rubinstein, E. (2001). "History of quinolones and their side effects.". Chemotherapy 47 Suppl 3: 3-8; discussion 44-8. PMID 11549783.  
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