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Toxic multinodular goitre
Classification and external resources
ICD-10 E05.2
ICD-9 242.3
DiseasesDB 13184
MedlinePlus 000317
eMedicine med/920

Toxic multinodular goitre (also known as toxic nodular goitre, toxic nodular struma) is a form of hyperthyroidism - where there is excess production of thyroid hormones. It is characterized by functionally autonomous nodules. It emerges insidiously from nontoxic multinodular goitre.

It is the second most common cause of hyperthyroidism after Graves disease.



Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:

Related eponym

Plummer's disease is named after the American physician Henry Stanley Plummer but refers to a single toxic nodule (adenoma) which may present with the background of a suppressed multinodular goitre.[1]


  1. ^ Plummer's disease eponymously named after Henry Stanley Plummer at Who Named It?

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