The Full Wiki

More info on Trichosanthes kirilowii

Trichosanthes kirilowii: Wikis


Note: Many of our articles have direct quotes from sources you can cite, within the Wikipedia article! This article doesn't yet, but we're working on it! See more info or our list of citable articles.


From Wikipedia, the free encyclopedia

Trichosanthes kirilowii
Scientific classification
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Cucurbitales
Family: Cucurbitaceae
Genus: Trichosanthes
Species: T. kirilowii
Binomial name
Trichosanthes kirilowii

Trichosanthes kirilowii is a flowering plant in the family Cucurbitaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name guālóu (simplified Chinese: ).


Chemical components

The plant is a source of the chemical compound trichosanthin.[1]

See also


Trichosanthin was purified from fresh Chinese root tubers of Trichosanthes kirilowii and evaluated for anti-HIV activity. Trichosanthin inhibited syncytium formation between infected H9 cells and uninfected Sup-T1 cells from 0.5 to 4 [mu]g/ml. Trichosanthin also inhibited HIV replication in H9 and CEM-SS cells at 1 [mu]g/ml, but was toxic for MT-4 cells (HTLV-1-positive), at doses greater than 0.25 [mu]g/ml. This new purification procedure confirms the anti-HIV activity of trichosanthin on some cell lines in different biological assays.

External links


Got something to say? Make a comment.
Your name
Your email address