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Trichosanthes kirilowii: Wikis

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Trichosanthes kirilowii
Scientific classification
Kingdom: Plantae
Division: Magnoliophyta
Class: Magnoliopsida
Order: Cucurbitales
Family: Cucurbitaceae
Genus: Trichosanthes
Species: T. kirilowii
Binomial name
Trichosanthes kirilowii
Maxim.[1]

Trichosanthes kirilowii is a flowering plant in the family Cucurbitaceae. It is one of the 50 fundamental herbs used in traditional Chinese medicine, where it has the name guālóu (simplified Chinese: ).

Contents

Chemical components

The plant is a source of the chemical compound trichosanthin.[1]

See also

References

Trichosanthin was purified from fresh Chinese root tubers of Trichosanthes kirilowii and evaluated for anti-HIV activity. Trichosanthin inhibited syncytium formation between infected H9 cells and uninfected Sup-T1 cells from 0.5 to 4 [mu]g/ml. Trichosanthin also inhibited HIV replication in H9 and CEM-SS cells at 1 [mu]g/ml, but was toxic for MT-4 cells (HTLV-1-positive), at doses greater than 0.25 [mu]g/ml. This new purification procedure confirms the anti-HIV activity of trichosanthin on some cell lines in different biological assays.

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